A 3.81 × 3.81 cm LaBr(Ce) detector based portable measurement setup has been developed for in situ gamma spectrometric survey of a contaminated site. This system is suitable for above- and below ground surface gamma spectrometric measurements of Cs. However, the minimum detectable activity concentration (MDAC), an important parameter of a measurement system, should be estimated for planning purposes of the gamma spectrometric survey. In this study, the MDAC of Cs for the measurement setup was investigated. The efficiency of the measurement setups was calculated from Monte Carlo simulations using MCNP code. The numerical model of the different studied set-ups, used in MCNP, performed well for the known cases. The results show that the MDAC varies with the position of the detector with respect to ground surface. A 5-20 min acquisition time, depending on the detector position, can be sufficient to get a MDAC of about 10% of the exemption limit of Cs (100 Bq/kg).
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http://dx.doi.org/10.1016/j.apradiso.2022.110247 | DOI Listing |
Cell Commun Signal
January 2025
IBMC - Instituto de Biologia Molecular E Celular, University of Porto, Porto, Portugal.
Background: Seipin is a protein encoded by the BSCL2 gene in humans and SEI1 gene in yeast, forming an Endoplasmic Reticulum (ER)-bound homo-oligomer. This oligomer is crucial in targeting ER-lipid droplet (LD) contact sites, facilitating the delivery of triacylglycerol (TG) to nascent LDs. Mutations in BSCL2, particularly N88S and S90L, lead to seipinopathies, which correspond to a cohort of motor neuron diseases (MNDs) characterized by the accumulation of misfolded N88S seipin into inclusion bodies (IBs) and cellular dysfunctions.
View Article and Find Full Text PDFAnal Chem
December 2024
Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
Point-of-care testing (POCT) involves administering rapid on-site analysis to provide fast biochemical testing results. POCT reduces delays in clinical decision-making and eliminates the need to transport and prepare clinical samples for immediate diagnosis or clinical intervention by healthcare professionals. Herein, a novel methodology integrating thin-layer chromatography-based two-dimensional separation with miniature mass spectrometry was developed for rapid on-site clinical analysis.
View Article and Find Full Text PDFAppl Radiat Isot
November 2024
Nuclear Physics Division, Bhabha Atomic Research Centre, Mumbai, 400 085, India.
The cumulative yield of the fission products within the mass range of 83-117 and 123-153 have been measured in the 6.61and 10.92 MeV quasi-mono-energetic neutron-induced fission of U by using an off-line γ-ray spectrometric technique.
View Article and Find Full Text PDFBiology (Basel)
October 2024
Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.
(1) Background: Chronic rhinosinusitis (CRS) is a common chronic inflammation of the nasal mucosa and the paranasal sinuses. The pathogenesis of chronic rhinosinusitis (CRS) is multifactorial and, as of yet, not well understood. (2) Methods: Nasal lavage fluid samples were collected from patients diagnosed with chronic sinusitis with nasal polyposis (CRSwNP) (n = 10) and individuals without sinusitis (control group) (n = 10) who had no nasal complaints.
View Article and Find Full Text PDFObjective: Aim: To identify appropriate methods for determining the content of radioactive and non-radioactive pulmotoxic xenobiotics in the ambient air of NPP equipment to ensure its reliability, radiation and environmental safety, as well as to reduce the risks of occupational pathologies for workers and protect people's health.
Patients And Methods: Materials and Methods: Analytical methods of analysis of modern methods of determining the content of radioactive and non-radioactive pulmonary toxic xenobiotics in the ambient air of NPP equipment.
Conclusion: Conclusions: a) during operation of NPP equipment, pulmotoxic xenobiotics enter the surrounding air, which can then enter the human respiratory system in the form of radioactive or non-radioactive substances; b) signif i cant methods of determining the content of pulmotoxic xenobiotics in the air are: gas chroma-tography; gas chromatography-mass spectrometry; liquid scintillation; photometric, ionometric, polarographic, titrometric, turbidimetric, atomic absorption, radiometric and γ-spectrometric measurements; c) radioactive pulmonotoxic xenobiotics cause radiation pathologies in the respiratory organs as a result of internal radioactive irradiation of the body; d) the effects of non-radioactive pulmotoxic xenobiotics are accompanied by irritation and inf l ammatory processes in the respiratory organs, as well as toxic swelling of the lungs; е) there is a connection between the presence of pulmotoxic xenobiotics in the air and the course of human respiratory diseases as a result of breathing such air.
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