The role of iron-regulated mitophagy in lipid metabolism is unclear. Recent work by Long, Sanchez-Martinez et al (2022) shows that iron chelation induces a primary change in lipid metabolism that promotes fat accumulation and precedes mitophagy.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108591 | PMC |
http://dx.doi.org/10.15252/embj.2022111238 | DOI Listing |
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