Functional hearing disorder (FHD) is one of the conditions that fall under the umbrella of Functional Neurological Disorders. FHD is characterized by a decrease in hearing sensitivity without correlation in standard audiological testing. In the general pediatric population, the prevalence of FHD is estimated at less than 2%. The prevalence is about 7% in children 6-17 years of age. Some authors, however, consider FHD the most common etiology of sudden onset bilateral hearing loss in children. The mean age at diagnosis of FHD is 11.3 years - the condition is rare below 7 years of age. FHD affects twice as many girls as boys. The loss tends to be of sudden onset, bilateral, impacts all frequencies to a similar degree, and can be associated with an identifiable psychosocial conflict. FHD can be diagnosed using two sets of tests: (1) behavioral tests: pure-tone and speech audiometry; and (2) physiological tests: immittance audiometry, otoacoustic emissions, auditory evoked potentials, and functional neuroimaging. The backbone of the treatment of FHD includes cognitive-behavioral therapy and as needed, psychiatric medications. In this paper, we review the diagnosis, treatment, differential diagnosis, and complications of FHD.
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http://dx.doi.org/10.1016/j.spen.2022.100956 | DOI Listing |
Restoring leg length during total hip arthroplasty (THA) for femoral neck fracture is challenging due to the lack of an intact femoral neck on the fractured side. Thus, templating methods typically use size of the intact contralateral hip to estimate length. Common reference points include the distance from the lesser trochanter to the center of the femoral head (LTC) and femoral head diameter (FHD).
View Article and Find Full Text PDFAm J Biol Anthropol
January 2025
Institute for Quantitative Social Science, Harvard University, Cambridge, Massachusetts, USA.
Objectives: Self-domestication theory and preliminary data suggest that western chimpanzees (Pan troglodytes verus) could have smaller brains than eastern chimpanzees (P. t. schweinfurthii), but no large-scale studies of chimpanzee endocranial volume (ECV) have tested this.
View Article and Find Full Text PDFFront Plant Sci
November 2024
Information Technology Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Chlorophyll content is a vital indicator for evaluating vegetation health and estimating productivity. This study addresses the issue of Global Ecosystem Dynamics Investigation (GEDI) data discreteness and explores its potential in estimating chlorophyll content. This study used the empirical Bayesian Kriging regression prediction (EBKRP) method to obtain the continuous distribution of GEDI spot parameters in an unknown space.
View Article and Find Full Text PDFClin Cancer Res
December 2024
Dana-Farber Cancer Institute, Boston, United States.
Purpose: FHD-609, a potent, selective, heterobifunctional degrader of bromodomain-containing protein 9 (BRD9), was evaluated for treatment of patients with advanced synovial sarcoma (SS) or SMARCB1-deficient tumors.
Patients And Methods: In this multinational, open-label, phase 1 study (NCT04965753), patients received FHD609 intravenously at escalating doses either twice weekly (BIW) (5 to 80 mg; n=40) or once weekly (QW) (40 to 120 mg; n=15).
Results: Fifty-five patients received FHD-609 for a median of 43 days.
Cureus
November 2024
Department of Applied Nutrition and Food Technology, Islamic University, Kushtia, BGD.
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