AI Article Synopsis
- Deep Transcranial Magnetic Stimulation (dTMS) is an FDA-approved non-invasive therapy that effectively treats depression and OCD.* -
- A study involving 29 OCD patients found that after 30 sessions of dTMS, all participants showed at least a 35% reduction in OCD symptoms, measured by the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS).* -
- QEEG data indicated significant decreases in theta, alpha, and beta brain rhythms, with the reduction in OCD severity linked to decreased beta activity, suggesting dTMS may alter brain oscillations related to treatment response.*
Article Abstract
Deep Transcranial Magnetic Stimulation (dTMS) is a non-invasive treatment cleared by FDA as a safe and efficient intervention for the treatment of depression and obsessive-compulsive disorder (OCD). In this retrospective single-center study, the effects of dTMS on the electrophysiological parameters and the clinical outcomes of patients with OCD were tested. Thirty sessions of dTMS were administered to 29 OCD patients (15 female and 14 male). Quantitative electroencephalography (QEEG) recordings and Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) were measured at baseline and endpoint. Paired sample t-test was used to measure the change in Y-BOCS scores and QEEG activity after dTMS practice. All 29 patients responded to the dTMS intervention by indicating at least 35% reduction in Y-BOCS scores. QEEG recordings revealed a significant decrease in theta, alpha and the beta rhythms. The decrease in the severity of OCD symptoms correlated with the decrease in beta activity at left central region. Historically, excess fast oscillations in OCD are correlated with the unresponsiveness to selective serotonin reuptake inhibitor (SSRI) treatment. We hypothesize that the decrease in the power of beta bands by deep TMS is related to the mechanism of the therapeutic response.
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| http://dx.doi.org/10.1177/15500594221095385 | DOI Listing |
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