Marine Demospongiae: A Challenging Treasure of Bioactive Compounds.

Mar Drugs

Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy.

Published: March 2022

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Article Abstract

In the last decades, it has been demonstrated that marine organisms are a substantial source of bioactive compounds with possible biotechnological applications. Marine sponges, in particular those belonging to the class of Demospongiae, have been considered among the most interesting invertebrates for their biotechnological potential. In this review, particular attention is devoted to natural compounds/extracts isolated from Demospongiae and their associated microorganisms with important biological activities for pharmacological applications such as antiviral, anticancer, antifouling, antimicrobial, antiplasmodial, antifungal and antioxidant. The data here presented show that this class of sponges is an exciting source of compounds, which are worth developing into new drugs, such as avarol, a hydroquinone isolated from the marine sponge , which is used as an antitumor, antimicrobial and antiviral drug.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032870PMC
http://dx.doi.org/10.3390/md20040244DOI Listing

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