Communication between the nervous system and immune system is important for regulating immunity in health and disease. Yu et al. (2022) show that neuropeptide Y and its homolog NPF serve as a "language" to facilitate crosstalk between these two systems across species, enabling neurons to downregulate harmful immune responses.
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| http://dx.doi.org/10.1016/j.neuron.2022.03.036 | DOI Listing |
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Simultaneous bone and nerve regeneration is important in facilitating osseointegration. However, regeneration of neural elements is often overlooked when designing orthopedic implants. Since nerves are electroactive tissues that regulate bone formation via neuropeptide release, developing photoelectric coating material on implants is optimal for neural-stimulated osteoblast activation.
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