Phenylpropanoids from and their anti-inflammatory activity.

J Asian Nat Prod Res

Key Laboratory of Basic and Application Research of Beiyao, (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin 150040, China.

Published: February 2023

Two new phenylpropanoids, 4-O-(1''-O-cis-caffeoyl)--glucopyran osyl-1-allyl-3-methoxy-benzene (), 4'-O-(1''-O-cis-caffeoyl)--glucopyranosyl-hydroxymegastigm-4-en-3-one (), together with nine known compounds were obtained from the leaves of . Their structures were elucidated based on spectroscopic methods, and comparing spectral data with those in literature. Meanwhile, their anti-inflammatory activities were evaluated on (LPS)-induced RAW 246.7 cells, and , , and showed better inhibitory effects with IC values of 17.19 ± 1.12, 18.15 ± 0.47, and 19.8 ± 0.95 μM, respectively.

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http://dx.doi.org/10.1080/10286020.2022.2066529DOI Listing

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