Electrochemical sensors to measure biomarkers from complex samples are a tried and tested technology with large untapped potential for addressing important public health needs.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066060PMC
http://dx.doi.org/10.15252/embr.202255096DOI Listing

Publication Analysis

Top Keywords

potential electrochemical
8
electrochemical biosensors
8
biosensors developing
8
developing novel
8
novel point-of-care
8
point-of-care diagnostics
8
electricity chemistry
4
chemistry biomarkers
4
biomarkers elegant
4
elegant simple
4

Similar Publications

Continuous decoupled redox electrochemical CO capture.

Nat Commun

December 2024

State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering, Sichuan University & Shenzhen University, Chengdu, P.R. China.

Electrochemical CO capture driven by renewable electricity holds significant potential for efficient decarbonization. However, the widespread adoption of this approach is currently limited by issues such as instability, discontinuity, high energy demand, and challenges in scaling up. In this study, we propose a scalable strategy that addresses these limitations by transforming the conventional single-step electrochemical redox reaction into a stepwise electrochemical-chemical redox process.

View Article and Find Full Text PDF

Redox-active Co(II) and Zn(II) Pincer Complexes as High-Capacity Anode Materials for Lithium-Ion Batteries.

Adv Sci (Weinh)

December 2024

Department of Chemistry and Research Institute of Molecular Alchemy, Gyeongsang National University, Jinju, 52828, South Korea.

To address the ongoing demand for high-performance energy storage devices, it is crucial to identify new electrode materials. Lithium-ion batteries (LIBs) store energy via the electrochemical redox process, so their electrode materials should have reversible redox properties for rechargeability. On that note, redox-active metal complexes are explored as innovative electrode materials for LIBs.

View Article and Find Full Text PDF

This study aims to demonstrate that redox couples, regardless of their electrical charges, are unnecessary for detecting and quantifying electroactive proteins using an electrochemical sensor functionalized with a molecularly imprinted polymer. Our approach involved designing a polydopamine imprinted biosensor for detecting bovine serum albumin as the model protein. Electrochemical measurements were conducted in a phosphate-buffered solution (PBS) and solutions containing the negatively charged hexacyanoferrate, the neutral ferrocene, or the positively charged hexaammineruthenium (III) probes.

View Article and Find Full Text PDF

Biomimetic gastric microtissue electrochemical biosensors for ovalbumin detection.

Biosens Bioelectron

December 2024

College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing, Jiangsu, 210023, PR China. Electronic address:

An innovative integrated three-dimensional (3D) bioprinted gastric microtissue electrochemical biosensor was developed in this study for the detection of allergen ovalbumin (OVA). In this system, OVA triggers the release of histamine from gastric microtissue, which then undergoes a redox reaction on the electrode surface, leading to an increase in the peak current. Gelatin methacrylate hydrogel serves as a scaffold for the 3D culture of RBL-2H3 and PC-12 cells for partially restoring allergic reactions in the human body in vitro.

View Article and Find Full Text PDF

Unlocking Mesoscopic Disorder in Graphitic Carbon with Spectroelectrochemistry.

Angew Chem Int Ed Engl

December 2024

University of Chicago Division of the Physical Sciences, Chemistry, 929 E 57th St, Gordon Center for Integrative Science, 60637, Chicago, UNITED STATES OF AMERICA.

Intrinsic structural and oxidic defects activate graphitic carbon electrodes towards electrochemical reactions underpinning energy conversion and storage technologies. Yet, these defects can also disrupt the long-range and periodic arrangement of carbon atoms, and thus the characterization of graphitic carbon electrodes necessitate in-situ atomistic differentiation of graphitic regions from mesoscopic bulk disorder. Here, we leverage the combined techniques of in-situ attenuated total reflectance infrared spectroscopy and first-principles calculations to reveal that graphitic carbon electrodes exhibit electric-field dependent infrared activity that is sensitive to the bulk mesoscopic intrinsic disorder.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!