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The effect of consumption of cranberry on adherence to feline uroepithelial cells in a blind randomised cross-over trial in cats.
J Vet Res
December 2024
Equipe de Recherche sur les Relations Matrice Extracellulaire-Cellule (ERRMECe) Laboratory, Site de St-Martin, CY Cergy Paris University, 95302 Cergy-Pontoise, France.
Introduction: is the most common uropathogen in humans, dogs and cats. Dietary consumption of cranberry () is known to be associated with a reduction in uropathogenic (UPEC) adhesion to human and canine urinary epithelial cell lines, but this has not been shown in cats.
Material And Methods: Six neutered domestic cats, one male and five females, were randomly fed three diets successively, one containing 0.
Asystematic review and meta-analysis of clinical prognostic factors linked to extravesical recurrence after radical nephroureterectomy to treat upper tract urothelial carcinoma.
Front Oncol
November 2024
Urology Department, Henan Provincial People's Hospital, Zhengzhou, China.
Objective: Numerous studies have investigated predictors of intravesical recurrence following radical nephrectomy (RNU) in patients with upper urinary tract uroepithelial carcinoma (UTUC). In contrast, extravesical recurrence (EUR) has received less focus. Consequently, this study aims to evaluate the significant predictors of EUR after RNU through a systematic review of the literature and a meta-analysis.
View Article and Find Full Text PDFType 1 fimbrial phase variation in multidrug-resistant asymptomatic uropathogenic Escherichia coli clinical isolates upon adherence to HTB-4 cells.
Folia Microbiol (Praha)
December 2024
Department of Biochemistry and Medical Biotechnology, School of Tropical Medicine, 108, C.R. Avenue, Kolkata, 700073, India.
The adherence of bladder uroepithelial cells, subsequent expression, and regulation of type 1 fimbrial genes (key mediator of attachment) in clinical multidrug-resistant uropathogenic Escherichia coli (MDR-UPECs) isolated from individuals with asymptomatic bacteriuria (ABU) remain unexplored till date. Therefore, this study aimed to investigate the underlying molecular mechanisms associated with the adherence of clinical MDR-ABU-UPECs to human a uroepithelial cell line (HTB-4), both in the absence and presence of D-Mannose. These investigations focused on phase variation, expression, and regulation of type 1 fimbriae and were compared to a prototype ABU-strain (E.
View Article and Find Full Text PDFD-mannose for preventing and treating urinary tract infections.
Cochrane Database Syst Rev
August 2022
Sydney School of Public Health, The University of Sydney, Sydney, Australia.
Background: Urinary tract infections (UTIs) are very common, affecting more than 7 million people worldwide. Whilst many people may only experience a single episode in their lifetime and are generally responsive to standard antibiotics, a significant proportion of adults and children (approximately 15% to 25%) are chronic symptomatic UTI sufferers. Certain population groups are at greater risk than others, such as immunosuppressed and people with chronic kidney disease.
View Article and Find Full Text PDFRegulation of gene transcription by GadE and other acid tolerance gene products.
Microbiology (Reading)
March 2022
University of Wisconsin - La Crosse, La Crosse, WI, USA.
Uropathogenic (UPEC) cause millions of urinary tract infections each year in the United States. Type 1 pili are important for adherence of UPEC to uroepithelial cells in the human and murine urinary tracts where osmolality and pH vary. Previous work has shown that an acidic pH adversely affects the expression of type 1 pili.
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