Complex research questions often need large samples to obtain accurate estimates of parameters and adequate power. Combining extant data sets into a large, pooled data set is one way this can be accomplished without expending resources. Measurement invariance (MI) modeling is an established approach to ensure participant scores are on the same scale. There are two major problems when combining independent data sets through MI. First, sample sizes will often be large leading to small differences becoming noninvariant. Second, not all data sets may include the same combination of measures. In this article, we present a method that can deal with both these problems and is user friendly. It is a combination of generating random normal deviates for variables missing completely in combination with assessing model fit using the root mean square error of approximation , based on the hypothesis that the difference between groups is not zero but small. We demonstrate the method by examining MI across eight independent data sets and compare the MI decisions of the traditional and approach. Our results show the approach has potential in combining educational data.
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http://dx.doi.org/10.1177/00131644211023567 | DOI Listing |
Hepatol Commun
November 2024
Human Immunology Laboratory, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, New South Wales, Australia.
Background: HCC develops in the context of chronic inflammation; however, the opposing roles the immune system plays in both the development and control of tumors are not fully understood. Mapping immune cell interactions across the distinct tissue regions could provide greater insight into the role individual immune populations have within tumors.
Methods: A 39-parameter imaging mass cytometry panel was optimized with markers targeting immune cells, stromal cells, endothelial cells, hepatocytes, and tumor cells.
Educ Psychol Meas
January 2025
Faculty of Psychology and Educational Sciences, KU Leuven, Campus KULAK, Kortrijk, Belgium.
Multidimensional Item Response Theory (MIRT) is applied routinely in developing educational and psychological assessment tools, for instance, for exploring multidimensional structures of items using exploratory MIRT. A critical decision in exploratory MIRT analyses is the number of factors to retain. Unfortunately, the comparative properties of statistical methods and innovative Machine Learning (ML) methods for factor retention in exploratory MIRT analyses are still not clear.
View Article and Find Full Text PDFFront Plant Sci
December 2024
Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, Taizhou University, Taizhou, China.
, native to North America, is an invasive species in many areas of the world, where it causes serious damage to natural ecosystems and economic losses. However, a dearth of genetic resources and molecular markers has hampered our understanding of its invasion history. Here, we assembled 40 complete chloroplast genomes of species, including 21 individuals, 15 individuals, and four individuals, the sizes of which ranged from 152,412 bp to 153,170 bp.
View Article and Find Full Text PDFSpat Stat
March 2024
United States Environmental Protection Agency, 200 SW 35th St, Corvallis, OR, USA.
Conductivity is an important indicator of the health of aquatic ecosystems. We model large amounts of lake conductivity data collected as part of the United States Environmental Protection Agency's National Lakes Assessment using spatial indexing, a flexible and efficient approach to fitting spatial statistical models to big data sets. Spatial indexing is capable of accommodating various spatial covariance structures as well as features like random effects, geometric anisotropy, partition factors, and non-Euclidean topologies.
View Article and Find Full Text PDFHypertension
January 2025
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, China. (F.W., Z.L., W.L., H.L., H.F., S.L., C.Z., Y.Z., S.M., C.W., Z.Z., W.F., J.Z., Q.Y., M.D., W.K., A.L., J.L., X.L., X.W., N.L., Y.C., K.Y., J.W.).
Background: Mechanosensitive Piezo1 channel plays a key role in pulmonary hypertension (PH). However, the role of Piezo2 in PH remains unclear.
Methods: Endothelial cell (EC)-specific knockout (, Tek-Cre; ) rats and primarily cultured pulmonary microvascular ECs were used to determine the role of Piezo2 in PH.
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