AI Article Synopsis
- A study evaluates a nurse navigation program aimed at improving treatment adherence and curing hepatitis C in patients with severe mental disorders, through a randomized controlled trial.
- Patients in the intervention group receive comprehensive support from mental health nurses, while the control group gets standard care from family doctors and specialists.
- The expected outcome is enhanced treatment access and adherence, potentially reducing the high prevalence of hepatitis C in this vulnerable population.
Article Abstract
Background: To evaluate the impact of a nurse navigation program on treatment adherence and resolution of hepatitis C infection in patients with severe mental disorder.
Methods: An open, randomized, controlled trial with blinded outcome assessment. The intervention group will engage in a nurse navigation program designed by mental health nurses. The program involves active screening for patients with severe mental disorder. The patients and caregivers included in the program will receive information, training, support and guidance throughout the treatment and recovery process, which involves different healthcare professionals and units. The control group will receive the standard of care, which includes follow-up by a family physician, referral to the hepatologist, serological testing, new referral to the hepatologist, onset of treatment, and follow-up. Multidisciplinary care will be provided along a coordinated and seamless clinical pathway led by a nurse navigator. The primary endpoints are total recovery (hepatitis C cure) and treatment adherence. Occurrence of symptoms of schizophrenia and health-related quality of life will be also recorded. Follow-up of patients will be performed three and six months after the administration of antiviral treatment. The study was authorised by the Ethics Committee of Malaga in December 2021. Funding was approved in March 2021.
Discussion: If this intervention is proven to be effective in improving treatment access and adherence, it will represent a step forward in addressing a chronic health issue that is 16 times more prevalent in the population with severe mental disease. Finally, this intervention may lead to the detection of undertreated HCV infection in this population of patients.
Trial Registration: This protocol has been registered in ClinicalTrials.gov with identifier code NCT04891445 on May 18, 2021.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020053 | PMC |
| http://dx.doi.org/10.1186/s12912-022-00870-w | DOI Listing |
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