Study of Neutrophil to Lymphocyte Ratio as Predictor of Prognosis in Acute Myocardial Infection in a Tertiary Hospital.

Unlabelled: Acute myocardial infarction (AMI) is a serious and fatal cardiovascular emergency. Previous studies linked an elevated leukocyte count with increased short-term and long-term risks of ischemic events and death in patients with acute coronary syndromes. Present study was aimed to study the role of neutrophil-to-lymphocyte ratio (NLR) in predicting the prognosis of acute myocardial infarction.

Material: Present study was retrospective, case record study, conducted in patients age >18 years, hospitalized & diagnosed as acute MI.

Observation: 145 cases were considered for present study. Majority of patients were from 51-60 years age group (35.17 %) followed by 61-70 years age group (27.59 %). Majority were male (84.14 %). High risk factors such as Smoking (69.66 %), Hypertension (57.24 %), Alcoholic (30.34 %) & Diabetes (22.07 %) were noted in study patients. On Admission Elevated TROP I levels were noted in 92.41 % patients. In hospital mortality was noted in 24 cases (16.55 %). In majority of cases ECG findings were Anterior Wall MI (28.28 %), Non ST Elevation MI (26.21 %) & Inferior Wall MI (17.93 %). In study cases majority had ST Elevated MI (61.38 %) followed by Non ST Elevated MI (26.21 %), Unstable Angina (6.9 %) & Stable Angina (5.52 %).Mean NLR of study cases was 5.48 ± 2.01. Significant relationship was noted with NSTEMI, STEMI & In-hospital Mortality in patients with high NLR (>4.7) (p<0.05).

Conclusion: Neutrophil to lymphocyte ratio is readily available clinical laboratory value and an independent predictor of prognosis in acute myocardial infarction as well as mortality related to acute myocardial infarction.