Lead is an environmental hazard; even small elevations in blood lead level can cause serious negative health effects in children, including irreversible impacts such as learning difficulties, attention disorders, and behavioral issues. Previous research has shown that some groups are at higher risk for lead poisoning including racial/ethnic minorities, those with low economic status, and immigrants, especially refugees. This systematic review explores recent literature studying disparities in lead poisoning in refugee children. Search terms were chosen with the assistance of a medical librarian, and two independent reviewers assessed articles using a PICOS criteria (Population, Intervention, Comparison, Outcome, Study Design) following the Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRIMSA-P) guidelines, a set of evidence-based minimum standards for reporting in systematic reviews. 321 article titles were reviewed, 61 abstracts screened, and 17 methods sections reviewed, ultimately including 13 studies. The studies found a high prevalence of elevated blood lead level among refugee populations when compared to reference populations. Both pre-migration and post-migration factors were identified as contributors to the disparity, and associations were identified between elevated blood lead levels and factors such as country of origin, age, and other health variables. Health providers and resettlement workers should be aware of these disparities and related factors. Testing, care, education and consistent follow-up should be provided.

Download full-text PDF

Source
http://dx.doi.org/10.1515/reveh-2022-0015DOI Listing

Publication Analysis

Top Keywords

blood lead
16
elevated blood
12
systematic review
12
lead levels
8
refugee children
8
lead level
8
lead poisoning
8
lead
7
levels refugee
4
children united
4

Similar Publications

is a foodborne pathogen linked to severe infections in infants and often associated with contaminated powdered infant formula. The RecA protein, a key player in DNA repair and recombination, also influences bacterial resilience and virulence. This study investigated the impact of deletion on the pathogenicity and environmental stress tolerance of BAA-894.

View Article and Find Full Text PDF

Clonal hematopoiesis JAKs up plaque formation.

J Clin Invest

January 2025

Department of Medicine, Division of Hematology/Oncology, and.

Clonal hematopoiesis (CH) is a condition in which hematopoietic stem cells (HSCs) acquire mutations seen in leukemia. While individuals with CH generally do not show signs of hematologic disease, the condition becomes more common with age and correlates with age-related diseases, especially cardiovascular disease (CVD). JAK2 mutations in HSCs can lead to CH and correlate with atherosclerosis, but the condition has been difficult to study because of challenges modeling the mutant cells at very low frequency.

View Article and Find Full Text PDF

High-Density Lipoprotein Lipid and Protein Cargo and Cholesterol Efflux Capacity Before and After Bariatric Surgery.

Arterioscler Thromb Vasc Biol

January 2025

Department of Medicine, Leon H. Charney Division of Cardiology (S.Z., B.-X.L., A.C., M.F., E.A.F., S.P.H.).

Background: Cholesterol efflux capacity (CEC) of HDL (high-density lipoprotein) is inversely associated with incident cardiovascular events, independent of HDL cholesterol. Obesity is characterized by low HDL cholesterol and impaired HDL function, such as CEC. Bariatric surgery, including Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), broadly leads to improved cardiovascular outcomes, but impacts on risk factors differ by procedure, with greater improvements in weight loss, blood pressure, and glycemic control after RYGB, but greater improvements in HDL cholesterol and CEC levels after SG.

View Article and Find Full Text PDF

The D-lactate enigma: exploring the inflammatory influence of D-lactate in cattle.

Front Vet Sci

December 2024

Laboratory of Inflammation Pharmacology and Immunometabolism, Institute of Pharmacology and Morphophysiology, Faculty of Veterinary Sciences, Universidad Austral de Chile, Valdivia, Chile.

D-lactic acidosis is associated with fermentative disturbances and is often marked by elevated levels of D-lactic acid in the blood, ruminal fluid, and synovial fluid in cattle. D-lactic acidosis is linked to various inflammatory manifestations, and although the causative factors have been extensively explored, the exact pathogenesis of the associated inflammation remains elusive. Notably, less attention has been given to D-lactate, a stereoisomer found in the plasma of affected animals, which may lead to D-lactic acidosis.

View Article and Find Full Text PDF

Effects of hypoxia on uteroplacental and fetoplacental vascular function during pregnancy.

Front Physiol

December 2024

Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

During pregnancy, marked changes in vasculature occur. The placenta is developed, and uteroplacental and fetoplacental circulations are established. These processes may be negatively affected by genetic anomalies, maternal environment (i.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!