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http://dx.doi.org/10.1177/10499091221090224 | DOI Listing |
J Am Chem Soc
December 2024
Department of Chemistry, Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, California 90089, United States.
The development of photoswitches that absorb low energy light is of notable interest due to the growing demand for smart materials and therapeutics necessitating benign stimuli. Donor-acceptor Stenhouse adducts (DASAs) are molecular photoswitches that respond to light in the visible to near-infrared spectrum. As a result of their modular assembly, DASAs can be modified at the donor, acceptor, triene, and backbone heteroatom molecular compartments for the tuning of optical and photoswitching properties.
View Article and Find Full Text PDFJ Bone Joint Surg Am
December 2024
Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Background: Although total hip and total knee arthroplasty are highly successful operations, the decision of whether and when to undergo surgery is highly subjective and discretionary, and specific guidelines regarding readiness for surgery remain elusive. The nature of these decisions underscores the importance of shared decision-making, which is founded on the concept that patients substantially contribute to determining their own readiness for surgery. The OPTION survey was developed as a conversation aid to facilitate shared decision-making in the context of total joint arthroplasty.
View Article and Find Full Text PDFInterdiscip Sci
December 2024
College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao, 266590, China.
The imperative development of point-of-care diagnosis for accurate and rapid medical image segmentation, has become increasingly urgent in recent years. Although some pioneering work has applied complex modules to improve segmentation performance, resulting models are often heavy, which is not practical for the modern clinical setting of point-of-care diagnosis. To address these challenges, we propose UltraNet, a state-of-the-art lightweight model that achieves competitive performance in segmenting multiple parts of medical images with the lowest parameters and computational complexity.
View Article and Find Full Text PDFTrop Med Infect Dis
December 2024
Department of Community Medicine, Osun State University, Osogbo 230101, Nigeria.
Providing tuberculosis preventive treatment (TPT) to close contacts of persons with TB is a core strategy recommended by WHO for the prevention and control of TB. Nigeria rolled out the 3-month Isoniazid-Rifampicin (3HR) shorter regimen TPT as a pilot for use among eligible adult and child contacts. This study assesses acceptance and completion rates of 3HR TPT among contacts and determines the perspectives of healthcare workers (HCWs) and contacts on acceptance and completion of 3HR TPT in Nigeria.
View Article and Find Full Text PDFToxins (Basel)
December 2024
Headache Center, Neurological Clinic, "L. Amaducci", AOUC Policlinico, Piazza G. Cesare, 11, 70124 Bari, Italy.
This Special Issue aims to provide an updated overview of the current state and future perspectives of botulinum toxin treatment for migraine [...
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