We report a 54-year-old man with treatment-resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005678PMC
http://dx.doi.org/10.1002/ccr3.5651DOI Listing

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