Deep neural networks (DNN) have remarkably progressed in applications involving large and complex datasets but have been criticized as a black-box. This downside has recently become a motivation for the research community to pursue the ideas of hybrid approaches, resulting in novel hybrid systems classified as deep neuro-fuzzy systems (DNFS). Studies regarding the implementation of DNFS have rapidly increased in the domains of computing, healthcare, transportation, and finance with high interpretability and reasonable accuracy. However, relatively few survey studies have been found in the literature to provide a comprehensive insight into this domain. Therefore, this study aims to perform a systematic review to evaluate the current progress, trends, arising issues, research gaps, challenges, and future scope related to DNFS studies. A study mapping process was prepared to guide a systematic search for publications related to DNFS published between 2015 and 2020 using five established scientific directories. As a result, a total of 105 studies were identified and critically analyzed to address research questions with the objectives: (i) to understand the concept of DNFS; (ii) to find out DNFS optimization methods; (iii) to visualize the intensity of work carried out in DNFS domain; and (iv) to highlight DNFS application subjects and domains. We believe that this study provides up-to-date guidance for future research in the DNFS domain, allowing for more effective advancement in techniques and processes. The analysis made in this review proves that DNFS-based research is actively growing with a substantial implementation and application scope in the future.
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http://dx.doi.org/10.1007/s10462-022-10188-3 | DOI Listing |
BMC Health Serv Res
November 2024
Department of Public Health and Community Medicine, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt.
BMC Health Serv Res
November 2024
Health Specialist in UNICEF Egypt CO, Cairo, Egypt.
Background: Improving death certification of Under 5 Mortality (U5M) is an important pre-requisite for improving child health. This study aimed to obtain a clear and comprehensive understanding of the process of death registration of U5M and address the challenges of accurate certification faced by physicians at hospitals and health offices.
Methods: A qualitative descriptive study was performed by conducting 10 Focus Group Discussions (FGDs) with physicians who are actively involved in the certification of U5M.
Natl Sci Rev
November 2024
CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Abnormal levels of zinc ions within endo-lysosomes have been implicated in the progression of Alzheimer's disease (AD), yet the detection of low-concentration zinc ions at the organelle level remains challenging. Here we report the design of an endo-lysosome-targeted fluorescent reporter, Znluor, for imaging endogenous zinc ions. Znluor is constructed from an amphiphilic DNA framework (DNF) with programmable size and shape, which can encapsulate zinc-responsive fluorophores within its hydrophobic nanocavity.
View Article and Find Full Text PDFTalanta
January 2025
College of Chemistry and Chemical Engineering, Key Laboratory of Shandong Provincial Universities for Functional Molecules and Materials, Qingdao University, Qingdao, 266000, China. Electronic address:
The controllable geometry and multifunctionality of DNA nano-bioreactors hold immense promise for disease diagnosis. Herein, a facile rolling circle amplification (RCA)-based crystallization method has been developed for highly efficient self-assembly of three-dimensional (3D) DNA nano-bioreactors, which show excellent cascade catalytic performance by confining bio-enzyme (glucose oxidase (GOx) used in this case) and copper ions (Cu) in DNA nanoflowers (DNFs) structure. The participation of Cu during the self-assembly process not only endows the nano-bioreactors (designated as GOx/Cu@DNFs) with inspiring peroxidase-like activity but also greatly improves the assembly efficiency and yield via the effective coordination between Cu and RCA-generated long concatemeric DNAs.
View Article and Find Full Text PDFACS Nano
October 2024
Department of Chemistry, Yonsei University, Seoul 03722, Republic of Korea.
In this study, we report a strategy for fabricating binary surface-enhanced Raman scattering (SERS) substrates composed of plasmonic Pt@Ag and Pt@Au truncated-octahedral (TOh) dual-rim nanoframes (DNFs) functioning as a "nanoalloy." Pt TOh frameworks act as a scaffold to develop nanoarchitectures with surface decoration using plasmonically active materials (i.e.
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