AI Article Synopsis
- The study focused on creating film-forming polymers to enhance the effectiveness of cleaned surfaces against bacteria.
- Antimicrobial polymers were synthesized from poly(ethylene-alt-maleic anhydride) and exhibited strong bacteria-killing properties when chlorine was incorporated, achieving significant reductions in E. coli and Staphylococcus aureus.
- The innovative approach involved grafting the polymer onto filter paper, which further improved its antibacterial performance, achieving a notable reduction of E. coli within 30 minutes.
Article Abstract
Our goal was to develop film-forming polymers to extend the antimicrobial lifetimes of cleaned and disinfected surfaces. Antimicrobial polymers were prepared by first reacting poly(ethylene-alt-maleic anhydride) with isopropylamine, partially consuming the anhydride groups, followed by hydrolysis to give water-soluble, highly anionic polyamide PC3. Chlorination with NaOCl gave PC3Cl with oxidative chlorine contents up to 9 wt%. Dried, 5 µm thick, PC3Cl films, gave log 4 reductions in the concentration of Escherichia coli or Staphylococcus aureus exposed to films. A unique feature of the maleic anhydride copolymer platform was the ability to form covalent grafts to surfaces via anhydride reactions. PC3 solution was impregnated into cellulosic filter paper, heated to form ester linkages with cellulose, followed by chlorination with sodium dichloroisocyanurate dihydrate giving grafted PC3Cl. The treated paper (0.3 wt% PC3Cl) gave a log 4 reduction of E. coli concentration in 30 min.
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| http://dx.doi.org/10.1016/j.colsurfb.2022.112487 | DOI Listing |
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