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| http://dx.doi.org/10.1053/j.ajkd.2022.02.019 | DOI Listing |
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Effects of statins on kidney function in older adults.
J Am Geriatr Soc
December 2024
School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Background: The effect of statin therapy on kidney function among older adults is unclear.
Objectives: To examine the association between statin use and changes in estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR), positive or negative, in an older adult cohort with versus without chronic kidney disease (CKD) at baseline.
Methods: This analysis included 18,056 participants aged ≥65 years with versus without CKD at baseline in a randomized trial of low-dose aspirin, who had no prior cardiovascular events, major physical disability, or dementia initially.
Objectives: To assess the clinical impact on generally healthy older Australians of changing from the 2009 CKD-EPI (CKD-EPI) to the 2021 CKD-EPI (CKD-EPI) equation for calculating the estimated glomerular filtration rate (eGFR).
Study Design: Secondary analysis of data from the prospective ASPirin in Reducing events in the Elderly (ASPREE) cohort study.
Setting, Participants: Australians aged 70 years or older living in the community and without life-limiting medical conditions, recruited 1 March 2010 - 31 December 2014 for the ASPREE trial.
Cardiovascular Disease in Patients with Chronic Kidney Disease: Current Understanding, Preventative Strategies, and Future Directions.
Cardiol Rev
December 2024
From the Department of Cardiovascular Disease, Case Western Reserve University School of Medicine, Cleveland, OH.
Article Synopsis
- * The review highlights the importance of understanding the unique cardiovascular risk profile in CKD patients, which includes factors like hypertension, albuminuria, and vascular calcification.
- * It discusses the potential benefits of various pharmacological treatments for CVD prevention, but emphasizes the need for more specific guidelines and further research to improve care for this high-risk group.
[The TG/HDL ratio as a marker of dyslipidemia among patients on maintenance hemodialysis. A cross-sectional study].
Urologiia
November 2024
University of Basrah, College of Medicine, Department of Medicine, Division of Nephrology, Basrah, Iraq.
Background And Objectives: Dyslipidemia is prevalent among patients with chronic kidney disease on maintenance hemodialysis. A high LDL is a known indicator of major adverse cardiovascular outcomes, but levels may be affected by malnutrition. A high TG/HDL ratio is another indicator of hard cardiovascular outcomes that should be sought carefully.
View Article and Find Full Text PDFRisk Factors for Major Bleeding among Patients with Chronic Kidney Disease Treated with Acetylsalicylic Acid.
Kidney Blood Press Res
December 2024
Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Introduction: Individuals with chronic kidney disease (CKD) are at increased risk of thrombotic events and bleeding. Acetylsalicylic acid (ASA), an effective antiplatelet agent, is one of the most frequently used medications for both primary and secondary prevention of cardiovascular disease (CVD). However, it can also contribute to bleeding events due to its inherent antiplatelet effect.
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