AI Article Synopsis
- * This study focused on determining the content and sulfation patterns of disaccharides from chondroitin sulfate/dermatan sulfate hybrid chains in various tissues of male and female rhesus monkeys.
- * Findings indicated that the main disaccharide units in these tissues were types A and C, while types E and iE were specifically found in tracheal and gastrointestinal tissues.
Article Abstract
Glycosaminoglycans (GAGs) are found in various tissues and are involved in many physiological functions. Since the rhesus monkey (Macaca mulatta) is the most widely used nonhuman primate in biomedical research, an understanding of the compositions of GAGs in their tissues is important. The aim of this study was to determine the content and sulfation pattern of disaccharides contained in several tissues of the rhesus monkey. The chondroitin sulfate (CS)/dermatan sulfate (DS) hybrid chain was extracted from several tissues of female and male rhesus monkeys. Compositional analysis was performed after digestion with chondroitinases ABC and ACI to reveal the sulfation pattern of the CS/DS hybrid chain. This study revealed that the major CS/DS disaccharide units present in the tissues were A and C types. The E and iE types were specifically distributed not only in the tracheal tissue but also in gastrointestinal tissues.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/bbb/zbac057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!