Our experiments indicate hyperpolarized proton signals in the entire structure of remdesivir are obtained due to a long-distance polarization transfer by -hydrogen. SABRE-based biological real-time reaction monitoring, by using a protein enzyme under mild conditions is carried out. It represents the first successful -hydrogen based hyperpolarization application in biological reaction monitoring.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981083 | PMC |
| http://dx.doi.org/10.1039/d2ra00062h | DOI Listing |
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