A mild method to access functionalized 2-iminothiazolines in a facile and efficient manner has been developed. The reaction started from 1,3-disubstituted thioureas and 1-bromo-1-nitroalkenes in the presence of triethylamine in THF and proceeded smoothly in air to afford 2-iminothiazoline derivatives in moderate to good yields.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693722 | PMC |
http://dx.doi.org/10.1039/d0ra00686f | DOI Listing |
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