An efficient cascade reaction involving sulfonylation and [2 + 3]-cycloaddition reactions of -dibromoalkenes with arylsulfonyl methyl isocyanides was described for the synthesis of 3-aryl-2,4-disulfonyl-1-pyrroles. The main highlight of this study is the introduction of a new dual-functional reactivity of arylsulfonyl methyl isocyanides as the sulfonyl source as well as a 1,3-dipolar reagent in the same reaction. This system is facilitated by CsCO mediation in DMSO and 100 °C conditions.
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| http://dx.doi.org/10.1039/d0ra10451e | DOI Listing |
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