Currently, there are more than 8200 amphibian species described, including the orders Anura (frogs and toads), Caudata (salamanders and newts) and Gymnophiona (caecilians). Amphibians have 3 heart chambers: 2 atria and 1 ventricle. Their heart anatomy, histology, and physiology are reviewed. The basic morphology of the heart is similar in all amphibians with some differences due to their lifestyle. Blood flow, blood mixing, and blood oxygenation show variation due to interindividual and interspecific differences. Finally, different diagnostic methods to investigate the amphibian heart are described and reported amphibian heart diseases are summarized, including genetic, congenital, infectious, and neoplastic heart diseases.
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http://dx.doi.org/10.1016/j.cvex.2022.01.002 | DOI Listing |
Biochem Biophys Res Commun
January 2025
Department of Biotechnology and Department of Integrative Food, Bioscience and Biotechnology (BK21 FOUR), Chonnam National University, Gwangju, 61186, South Korea. Electronic address:
Methylergometrine has widely been used pharmacologically to treat conditions such as pain, addiction, vasoconstriction, migraines, and Parkinson's disease. Despite its side effects, it is used as a therapeutic agent and research material for various diseases based on its natural potential; however, the regulatory effect of its interaction with the nicotinic acetylcholine receptor (nAChR) has not yet been investigated. The α3β4 nAChR is an ion channel essential for neurotransmission within the sympathetic, parasympathetic, and autonomic nervous systems.
View Article and Find Full Text PDFEcol Evol
December 2024
The Observation and Research Field Station of Taihang Mountain Forest Ecosystems of Henan Province, College of Life Sciences Henan Normal University Xinxiang China.
The transition from water to land of amphibians is evolutionarily significant in the history of vertebrates, and immunological adaptation is an important challenge for amphibians to respond to the dramatic changes of the environmental pathogens during their origin and diversification. Toll-like receptors (TLRs) are important pattern recognition receptors for the innate immune response and TLRs signaling pathway play essential roles in the immune responses to pathogens and inflammatory reaction. However, the evolutionary patterns and molecular mechanisms underlying their adaptation in amphibians are poorly documented to date.
View Article and Find Full Text PDFVet Res Commun
November 2024
Institute of Zoology, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Dev Comp Immunol
January 2025
Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, 252-0880, Japan.
The clonal triploid ginbuna crucian carp Carassius auratus langsdorfii, a naturally occurring gynogenetic fish, is suitable for cell transplantation studies to reveal the roles of stem cells and immune cells. To ensure long-term traceability of donor cells within recipient fish, we have established a transgenic ginbuna line that expresses green fluorescent protein (GFP). The Xenopus laevis ef1a promoter was introduced for regulating GFP expression.
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