Three new furanoxanthones, macochinxanthones A-C (-) and sixteen known xanthones (-) were isolated from the roots of Their structures were elucidated by spectroscopic analysis including NMR, UV and IR, as well as mass spectrometry. Chiral-phase HPLC analysis of - revealed that they were scalemic mixtures with an enantiomeric excess (ee) of 0.05%, 36.8% and 8%, respectively. Most of the isolated xanthones exhibited potent cytotoxicity against four cancer cell lines (KB, HelaS3, A549 and HepG2) with IC values in the range of 1.29-90.15 M. In addition, many of them displayed antibacterial activity against Gram-positive bacteria and Methicillin resistant (MRSA) with MIC values in the range of 4-128 g/mL.
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