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To study the antitumor activity and action mechanism of Ru(II) polypyridyl plumbagin (PLN) complexes, four complexes [Ru(PLN)(DMSO)]Cl (Ru1), [Ru(bpy)(PLN)](PF) (bpy is bipyridine) (Ru2), [Ru(phen)(PLN)](PF) (phen is 1,10-phenanthroline) (Ru3), and [Ru(DIP)(PLN)](PF) (DIP is 4,7-diphenyl-1,10-phenanthroline) (Ru4) were obtained and fully characterized. Lipophilicity, cellular uptake and cytotoxicity of these Ru(II) complexes are in the order of: Ru1
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http://dx.doi.org/10.1016/j.ejmech.2022.114312 DOI Listing Publication Analysis
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