AI Article Synopsis

  • Three patients with paroxysmal nocturnal hemoglobinuria (PNH) showed extensive hepatic venous thrombosis through ultrasound scanning.
  • This diagnosis was validated by X-ray venography, revealing that two patients had no significant clinical symptoms other than minor elevation of liver enzymes.
  • The study highlights that ultrasound is an effective method for detecting this critical condition, suggesting that hepatic venous thrombosis may occur more frequently in PNH patients than previously thought.

Article Abstract

Extensive hepatic venous thrombosis was demonstrated by ultrasonic scanning in three patients with paroxysmal nocturnal haemoglobinuria (PNH). The ultrasonography results were confirmed by X-ray venography. Two of these patients were without clinical symptoms of hepatic involvement apart from a slight increase in transaminases. This study indicates, firstly, that ultrasonic scanning is a rapid and reliable diagnostic tool in monitoring patients for this serious and often fatal complication, and, secondly, that hepatic venous thrombosis may be a more common complication in PNH than previously assumed.

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http://dx.doi.org/10.1111/j.1365-2141.1986.tb02235.xDOI Listing

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