Rapid scaling of semiconductor devices has led to an increase in the number of processor cores and integrated functionalities onto a single chip to support the growing demands of high-speed and large-volume consumer electronics. To meet this burgeoning demand, an improved interconnect capacity in terms of bandwidth density and active tunability is required for enhanced throughput and energy efficiency. Low-loss terahertz silicon interconnects with larger bandwidth offer a solution for the existing inter-/intrachip bandwidth density and energy-efficiency bottleneck. Here, a low-loss terahertz topological interconnect-cavity system is presented that can actively route signals through sharp bends, by critically coupling to a topological cavity with an ultrahigh-quality (Q) factor of 0.2 × 10 . The topologically protected large Q factor cavity enables energy-efficient optical control showing 60 dB modulation. Dynamic control is further demonstrated of the critical coupling between the topological interconnect-cavity for on-chip active tailoring of the cavity resonance linewidth, frequency, and modulation through complete suppression of the back reflection. The silicon topological cavity is complementary metal-oxide-semiconductor (CMOS)-compatible and highly desirable for hybrid electronic-photonic technologies for sixth (6G) generation terahertz communication devices. Ultrahigh-Q cavity also paves the path for designing ultrasensitive topological sensors, terahertz topological integrated circuits, and nonlinear topological photonic devices.
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http://dx.doi.org/10.1002/adma.202202370 | DOI Listing |
Chaos
January 2025
Department of Cognitive Sciences, University of California, Irvine, California 92617, USA.
We propose a novel approach to investigate the brain mechanisms that support coordination of behavior between individuals. Brain states in single individuals defined by the patterns of functional connectivity between brain regions are used to create joint symbolic representations of brain states in two or more individuals to investigate symbolic dynamics that are related to interactive behaviors. We apply this approach to electroencephalographic data from pairs of subjects engaged in two different modes of finger-tapping coordination tasks (synchronization and syncopation) under different interaction conditions (uncoupled, leader-follower, and mutual) to explore the neural mechanisms of multi-person motor coordination.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Columbia University, New York, NY, USA.
Background: As high as 50% of Alzheimer's disease (AD) patients experience "sundowning", which refers to an increased severity of neuropsychiatric symptoms (NPS), including agitation, confusion, and anxiety, selectively in the evening. Although sundowning significantly influences the decision to institutionalize patients, few preclinical models of this phenomenon exist and the underlying neural mechanisms are unknown. Here, we establish a model of sundowning by phenotyping the sleep-wake cycle and anxiety and exploratory behavior at different times of day in an AD mouse model.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Center for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center, New York, NY, USA.
Background: Stage III activated microglia have been associated with Alzheimer's Disease (AD) and cognitive decline. Separately, recent single-cell RNA-sequencing revealed CD74 as a marker gene that is enriched in immunologically active microglial subtypes associated with AD.
Method: Post mortem tissue sections from the dorsolateral prefrontal cortex were stained simultaneously for (1) CD74, (2) IBA1 (a general microglial marker that outlines cellular processes), and (3) phosphoTau (AT8 antibody) to locate Tau proteinopathy.
Phys Rev Lett
December 2024
Department of Physics, University of Texas at Austin, Austin, Texas 78712, USA.
The topological magnetoelectric effect (TME) is a defining property of three-dimensional Z_{2} topological insulators that was predicted on theoretical grounds more than a decade ago, but has still not been directly measured. In this Letter we propose a strategy for direct measurement of the TME and discuss the precision of the effect in real devices with charge and spin disorder.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
State Key Laboratory of High Field Laser Physics and CAS Center for Excellence in Ultra-intense Laser Science, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai, 201800, China.
We have observed the Berry phase effect associated with interband coherence in topological surface states (TSSs) using two-color high-harmonic spectroscopy. This Berry phase accumulates along the evolution path of strong field-driven electron-hole quasiparticles in electronic bands with strong spin-orbit coupling. By introducing a secondary weak field, we perturb the evolution of Dirac fermions in TSSs and thus provide access to the Berry phase.
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