Purpose: It is unknown whether surgery for endometriosis or recurrence of endometriosis affects obstetric outcomes.

Methods: A total of 208 pregnant women with a history of endometriosis were analyzed. Patients who had endometriomas >3 cm and no history of laparoscopic surgery for endometriosis were defined as non-surgery group ( = 60), while those who had a history of surgery for endometriosis ( = 148) were defined as surgery group. We investigated the obstetric outcomes in 208 patients according to with or without postoperative recurrence of endometriosis and the time from surgery to pregnancy.

Results: Among 177 cases of on-going pregnancy, in surgery group, there were lower prevalence of placenta previa compared with non-surgery group (8.5% vs. 23.4%;  = 0.020). Subgroup analysis revealed a decreased prevalence of placenta previa in postoperative non-recurrence group (6.0%:  = 0.007) compared with non-surgery (23.4%) and postoperative recurrence group (28.6%). Placenta previa was more prevalent in the patients who got pregnant more than 2 years after surgery (20.0%) than the patients who got pregnant within 2 years (2.4%:  = 0.002). Multivariate analysis revealed that the surgery was associated with a reduction in placenta previa (OR: 0.32, 95% CI [0.11-0.90];  = 0.032).

Conclusions: Pregnancy within two years after laparoscopic surgery for endometriosis may reduce placenta previa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986974PMC
http://dx.doi.org/10.1002/rmb2.12456DOI Listing

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