AI Article Synopsis
- KP (Klebsiella pneumoniae) is the leading cause of endogenous endophthalmitis (EE) in Asia, and this study looks at eight cases from France, indicating it may be on the rise in Europe.
- Researchers analyzed EE cases from 2014 to 2021, finding that 24% were caused by KP, primarily the hypervirulent strain, with most cases occurring recently.
- Patients with KP EE often had multiple infections outside the eyes, particularly notable liver abscesses, and a significant portion also experienced cerebral complications, with poor visual outcomes for all involved.
Article Abstract
Introduction: (KP) is the most common cause of endogenous endophthalmitis (EE) in Asia, but data in Europe are scarce. We describe eight cases of KP EE compared to a cohort of EE in a French center.
Methods: EE cases were retrospectively studied between January 2014 and January 2021. KP EE cases were analyzed to assess clinical, microbiological features, and outcome.
Results: Among the 33 EE cases identified, the first causative agent (24%, = 8) was KP, mainly (7/8) with hypervirulent phenotype (hvKP). All but one of these cases occurred from December 2019 to January 2021. Contrary to non-KP patients, KP patients had multiple extraocular infective foci ( = .006), all presented with liver abscesses ( < .001), 50% had cerebral involvement ( = .13). Visual outcome was poor in both groups.
Conclusion: KP is an emerging cause of EE in a French center, consistently associated with liver abscesses, frequent cerebral involvement, and predominance of hvKP strains.
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| http://dx.doi.org/10.1080/09273948.2022.2061521 | DOI Listing |
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