While ophthalmic manifestations of lupus are common, a myopic shift is a rare manifestation of systemic lupus erythematosus (SLE). An acute myopic shift is defined as a progressive worsening of nearsighted vision within a short time frame. Here, we describe the unique presentation of a young woman with a lupus-induced acute myopic shift. The patient presented with blurry vision and bleeding gums with a previous abnormal lymph node biopsy to rule out ocular lymphoma or leukemia. Her baseline prescription prior to coming in was -4.0D in both eyes. Upon exam, she presented with vision worsening: -7.0D in the right eye and -8.2D in the left eye. After completing blood laboratory tests, it became clear that she had pancytopenia, kidney damage, and elevated inflammatory markers pointing towards lupus. A diagnosis of acute binocular myopic shift induced by systemic lupus erythematosus was made.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989369 | PMC |
http://dx.doi.org/10.7759/cureus.22961 | DOI Listing |
Cornea
January 2025
Department of Ophthalmology, Rothschild Foundation, Paris, France; and.
Purpose: The purpose of this study was to investigate the effect of hypoxia and hypobaric conditions on refraction and central corneal thickness on healthy corneas during an ascent without oxygen supplementation above 7000 m (23 000 ft).
Methods: Twelve multinational mountaineers were included in a prospective observational cohort study during an expedition to the Korzhenevskoi Peak (7105 m). The two patients excluded from the study had a history with keratoconus or were current wearers of rigid contact lenses.
Asia Pac J Ophthalmol (Phila)
January 2025
National Institute of Cancer Research, National Health Research Institutes, Chinese Taipei. Electronic address:
Purpose: To investigate whether premyopia is a risk factor for myopia onset and whether outdoor activities can protect against myopia development in premyopic children in the Recess Outside Classroom (ROC) study.
Methods: Nonmyopic schoolchildren aged 7 to 11 years were recruited from two schools in Taiwan. One school implemented the ROC program, which encouraged children to go outdoors during recess.
Invest Ophthalmol Vis Sci
January 2025
School of Psychology and Public Health, La Trobe University, Melbourne, Australia.
Purpose: Prolonged exposure to broadband light with a short-wavelength (blue) or long-wavelength (orange/red) bias is known to impact eye growth and refraction, but the mechanisms underlying this response are unknown. Thus, the present study investigated the effects of broadband blue and orange lights with well-differentiated spectrums on refractive development and global flash electroretinography (gfERG) measures of retinal function in the chick myopia model.
Methods: Chicks were raised for 4 days with monocular negative lenses, or no lens, under blue, orange, or white light.
Ophthalmology
January 2025
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Shandong Academy of Eye Disease Prevention and Therapy, Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Shandong Provincial Clinical Medical Research Center of Optometry and Children Visual Impairment Prevention and Control, Shandong Engineering Technology Research Center of Visual Intelligence, Shandong Institute of Children Health and Myopia Prevention and Control, Shandong, China; Shandong University of Traditional Chinese Medicine, Shandong, China; Ophthalmology & Optometry Medical School, Shandong University of Traditional Chinese Medicine, Shandong, China. Electronic address:
Purpose: To assess the efficacy of a behavioral intervention using Eye-Use Monitoring technology to delay the onset and progression of myopia in children.
Design: A prospective, cluster-randomized, parallel-groups, examiner-masked, clinical trial (Chinese Clinical Trial Registry, ChiCTR2100052101).
Participants: A total of 413 children from grades 2 to 4 in Shandong, China, from October 2021 to December 2023 were randomized by class into three groups: reminder & feedback (6 classes, 156 children), reminder-only (5 classes, 147 children), and control (3 classes, 110 children).
Purpose: To evaluate the clinical outcome of laser-assisted surgical correction of high hyperopic or mixed astigmatism using small incision intrastromal lenticule rotation (SMILERO) alone or combined with photorefractive keratectomy (PRK).
Methods: This retrospective case series enrolled 25 eyes with high astigmatism that underwent SMILERO surgery. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected near visual acuity (UNVA), manifest refraction, central corneal thickness, and corneal higher order aberrations were analyzed before surgery and after 3, 6, and 12 months of follow-up.
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