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Normalization of Retinal Birefringence Scanning Signals.
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December 2024
Ophthalmic Instrumentation Development Lab, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Wilmer 233, 600 N. Wolfe St., Baltimore, MD 21287, USA.
Signal amplitudes obtained from retinal scanning depend on numerous factors. Working with polarized light to interrogate the retina, large parts of which are birefringent, is even more prone to artifacts. This article demonstrates the necessity of using normalization when working with retinal birefringence scanning signals in polarization-sensitive ophthalmic instruments.
View Article and Find Full Text PDFIntragroup and Intergroup Pairwise Key Predistribution for Wireless Sensor Networks.
Sensors (Basel)
December 2024
School of Information Science and Technology, Guangdong University of Foreign Studies, Guangzhou 510420, China.
The major task of a wireless sensor network (WSN) is data collection. Key predistribution (KP) is to establish pairwise keys for secure communication in a WSN, such that all collected data could be securely sent to a backend database. Most research on KP-like schemes is dedicated to enhancing resiliency against node capture attack (NA) and retaining the link connectivity in the meantime.
View Article and Find Full Text PDFCa/Calmodulin-Dependent Protein Kinase II (CaMKII) Regulates Basal Cardiac Pacemaker Function: Pros and Cons.
Cells
December 2024
Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, National Institute of Health, Baltimore, MD 21224, USA.
The spontaneous firing of the sinoatrial (SA) node, the physiological pacemaker of the heart, is generated within sinoatrial nodal cells (SANCs) and is regulated by a "coupled-clock" pacemaker system, which integrates a "membrane clock", the ensemble of ion channel currents, and an intracellular "Ca clock", sarcoplasmic reticulum-generated local submembrane Ca releases via ryanodine receptors. The interactions within a "coupled-clock" system are modulated by phosphorylation of surface membrane and sarcoplasmic reticulum proteins. Though the essential role of a high basal cAMP level and PKA-dependent phosphorylation for basal spontaneous SANC firing is well recognized, the role of basal CaMKII-dependent phosphorylation remains uncertain.
View Article and Find Full Text PDFWhat Is Truly Informed Consent in Medical Practice and What Has the Perception of Risk Got to Do with It?
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SHARE-Centre for Resilience in Healthcare, Faculty of Health Sciences, University of Stavanger, N-4036 Stavanger, Norway.
Making decisions about risk, describing and appropriately explaining risk in medical practice is complex for patients and professionals. In this paper, we investigate how the concept of consent is practiced differently in the UK and Norway and discuss pros and cons of the chosen approaches from a patient safety culture perspective. We argue that consent is a fundamental part of the safety culture and influence on health system functioning and patient and staff safety.
View Article and Find Full Text PDFA debate on whether drug courts be opened in India: Considerations and pragmatic suggestions.
Indian J Psychiatry
November 2024
National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India.
Drug courts are specialized programs from the courts that aim to offer a chance to individuals with substance-related problems encountering law enforcement to take treatment rather than face incarceration. The aim of this debate is to critically debate the utility, applicability, and feasibility of drug courts in India. This is a theoretical debate based on the existing evidence and considerations of ground realities in the country.
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