AI Article Synopsis
- The study assessed the health effects of lead exposure on 78 battery workers compared to 78 non-exposed individuals.
- Blood samples were collected to evaluate kidney, liver, and blood cell functions, revealing that the battery workers had higher lead levels and notable decreases in several hematological parameters.
- The exposed group also showed elevated liver and kidney damage markers, suggesting that excessive lead exposure can lead to significant health issues related to blood, liver, and kidney function.
Article Abstract
The purpose of this study was to evaluate the hematotoxic, hepatotoxic and nephrotoxic responses following lead exposure among battery workers. . Seventy-eight battery workers exposed to lead and 78 non-exposed subjects were studied. Fasting blood samples were collected to assess kidney and liver function and hematological parameters. To determine the breathing zone and blood lead levels (BLLs), the samples were analyzed in accordance with NIOSH methods 7082 and 8003, respectively. . The battery workers had significantly higher breathing zone lead and BLLs than the non-exposed group. In battery workers, most hematological parameters, including red blood cells, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration, have significantly decreased. In contrast, the white blood cell count has shown a significant increase as compared to the controls. The mean levels of alanine aminotransferase and aspartate aminotransferase as biomarkers of liver damage and the creatinine serum levels as a result of renal failure were significantly higher in the exposed group than in the non-exposed group. These observations indicate that occupational exposure to lead exceeding its current threshold limit value and biological exposure index is associated with hematological symptoms and liver and kidney dysfunction.
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| http://dx.doi.org/10.1080/10803548.2022.2064090 | DOI Listing |
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