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Which Training Intensity Distribution Intervention will Produce the Greatest Improvements in Maximal Oxygen Uptake and Time-Trial Performance in Endurance Athletes? A Systematic Review and Network Meta-analysis of Individual Participant Data.
Sports Med
January 2025
Department of Sport Science and Physical Education, Faculty of Health and Sport Sciences, University of Agder, Kristiansand, Norway.
Background: Endurance athletes tend to accumulate large training volumes, the majority of which are performed at a low intensity and a smaller portion at moderate and high intensity. However, different training intensity distributions (TID) are employed to maximize physiological and performance adaptations.
Objective: The objective of this study was to conduct a systematic review and network meta-analysis of individual participant data to compare the effect of different TID models on maximal oxygen uptake (VO) and time-trial (TT) performance in endurance-trained athletes.
Head-to-Head comparison of [F]FDG, [F]FMZ, and [F]SynVesT-1 positron emission tomography imaging in patients with drug-resistant epilepsy.
Eur J Nucl Med Mol Imaging
January 2025
Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Purpose: The loss of synaptic vesicle glycoprotein 2 A (SV2A) can lead to dysfunction of GABAergic neurons, but a direct comparison of SV2A and GABA receptor densities in humans has not been assessed. This study evaluated SV2A and GABA receptor abnormalities in patients with drug-resistant epilepsy (DRE) and compared the patterns to glucose hypometabolism.
Methods: Eleven patients with DRE were retrospectively recruited and underwent PET imaging with [F]fluorodeoxyglucose ([F]FDG), [F]Flumazenil (FMZ), and [F]SynVesT-1.
Structural Basis and Mechanism of a Unique Haemophore in the Haem-Iron Acquisition by Riemerella anatipestifer.
Adv Sci (Weinh)
January 2025
Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, 611130, China.
Several bacterial pathogens employ haemophores to scavenge haem from host haemoprotein to obtain an iron source. However, no homologues of well-characterized haemophores are found in Riemerella anatipestifer, a bacterium belonging to the order Flavobacteriales that encodes haem uptake systems. Herein, a unique haemophore RhuH is characterized in this bacterium.
View Article and Find Full Text PDFGenome-wide identification, characterization and expression pattern analysis of HAK/KUP/KT potassium transporter gene family in potato.
Front Plant Sci
January 2025
College of Agronomy, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, China.
The HAK/KUP/KT (High-affinity K transporters/K uptake permeases/K transporters) is the largest and most dominant potassium transporter family in plants, playing a crucial role in various biological processes. However, our understanding of HAK/KUP/KT gene family in potato ( L.) remains limited and unclear.
View Article and Find Full Text PDFA regional program evaluation of the Stanford Chronic Pain Self-Management Program in Eastern Ontario, Canada.
Can J Pain
January 2025
Bruyère Research Institute, Ottawa, Ontario, Canada.
Background: Health care providers often struggle to treat patients with chronic pain. One potential solution is to facilitate access to programs and tools that develop patients' skills and confidence in managing their own care.
Aims: This study aimed to describe the uptake of the Chronic Pain Self-Management Program (CPSMP) in Eastern Ontario and evaluate the effectiveness of the program in the acquisition of knowledge, confidence, and skills required to manage chronic pain, as measured by the Patient Activation Measure (PAM).
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