Plant-Derived Nanoscale-Encapsulated Antioxidants for Oral and Topical Uses: A Brief Review.

Int J Mol Sci

Department of BioNano Technology, Gachon University, Seongnam-daero 1342, Sujeong-gu, Seongnam-si 13120, Korea.

Published: March 2022

Several plant-based nanoscale-encapsulated antioxidant compounds (rutin, myricetin, β-carotene, fisetin, lycopene, quercetin, genkwanin, lutein, resveratrol, eucalyptol, kaempferol, glabridin, pinene, and whole-plant bio-active compounds) are briefly introduced in this paper, along with their characteristics. Antioxidants' bioavailability has become one of the main research topics in bio-nanomedicine. Two low patient compliance drug delivery pathways (namely, the oral and topical delivery routes), are described in detail in this paper, for nanoscale colloidal systems and gel formulations. Both routes and/or formulations seek to improve bioavailability and maximize the drug agents' efficiency. Some well-known compounds have been robustly studied, but many remain elusive. The objective of this review is to discuss recent studies and advantages of nanoscale formulations of plant-derived antioxidant compounds.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998173PMC
http://dx.doi.org/10.3390/ijms23073638DOI Listing

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