In the last decades, nanotechnology has been used in a wide range of biomedical applications, both diagnostic and therapeutic. In this scenario, imaging techniques represent a fundamental tool to obtain information about the properties of nanoconstructs and their interactions with the biological environment in preclinical and clinical settings. This paper reviews the state of the art of the application of magnetic resonance imaging in the field of nanomedicine, as well as the use of nanoparticles as diagnostic and therapeutic tools, especially in cancer, including the characteristics that hinder the use of nanoparticles in clinical practice.
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http://dx.doi.org/10.3390/cancers14071626 | DOI Listing |
Surg Radiol Anat
December 2024
Department of Neurosurgery, Nakamura Memorial Hospital, South 1, West 14, Chuo-Ku, Sapporo, Hokkaido, 060-8570, Japan.
Purpose: Although both accessory middle cerebral artery (MCA) of distal origin and anterior communicating artery (ACoA) duplication are not rare anatomical variations, their combination is extremely rare and there are only a few reports of such combinations.
Methods: We report a case of distal origin accessory MCA associated with ACoA duplication diagnosed by magnetic resonance angiography (MRA).
Results: A 63-year-old man visited another hospital for screening examinations for cerebrovascular disease.
Eur J Med Res
December 2024
Department of Neurosurgery, Neuromedicine Center, Beijing Shijitan Hospital, Capital Medical University, No. 10, Tieyi Road, Yangfangdian, Haidian District, Beijing, 100038, People's Republic of China.
Background: Full-endoscopic microvascular decompression (fE-MVD) is an emerging treatment option for trigeminal neuralgia (TN). However, the risk factors associated with postoperative recurrence of TN after fE-MVD procedure remain controversial. The aim of the present study was to summarize the surgical technique of fE-MVD for the treatment of TN and to develop a predictive model for recurrence at 1 year postoperatively based on independent risk factors.
View Article and Find Full Text PDFPsychopharmacology (Berl)
December 2024
Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, Kings College London, De Crespigny Park, London, SE5 8AF, UK.
Rationale: Working memory impairment is a prominent feature of schizophrenia which predicts clinical and functional outcomes. Preclinical data suggest histamine-3 receptor (H3R) expression in cortical pyramidal neurons may have a role in working memory, and post-mortem data has found disruptions of H3R expression in schizophrenia.
Objectives: We examined the role of H3R in vivo to elucidate its role on working memory impairment in schizophrenia.
Abdom Radiol (NY)
December 2024
Massachusetts General Hospital, Boston, USA.
Adnexal masses are frequently encountered in general practice. Whether employing CT, US, or MRI, imaging plays a pivotal role in guiding appropriate treatment for patients with adnexal masses, potentially minimizing the need for surgery in benign cases and expediting the management of those with suspected malignancy. Accurately distinguishing benign from malignant adnexal masses can be challenging due to the confined pelvic space and the proximity of organs, making it difficult to determine their organ of origin or to distinguish tissue characteristics and imaging features.
View Article and Find Full Text PDFBMC Infect Dis
December 2024
Central Laboratory, Chongqing Public Health Medical Centre, Chongqing, China.
Background: In acquired immunodeficiency syndrome patients, Talaromyces marneffei infections are mostly disseminated and may involve the skin, mucosa, respiratory system, digestive system, lymphatic system, and as some reports indicate, the nervous system. Mp1p, a cell wall-specific polysaccharide in Talaromyces marneffei, is used for laboratory diagnosis of Talaromyces marneffei in blood and urine samples. However, Cerebrospinal fluid Mp1p diagnosis of Talaromyces marneffei central nervous system infection has not been reported.
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