Heart disease remains the leading cause of death among men and women in the world. The majority of cardiac morbidity worldwide is secondary to atherosclerotic coronary disease. In this article, we discuss our experience using dual exposure, dual-energy lateral chest x-ray (CXR) technique to detect coronary calcium. Similar to other reports demonstrating opportunistic detection on imaging studies, here we demonstrate the added value of detection of coronary calcium on the lateral CXR. This technique reinforces the importance of "knowing where to look" and to recognize the appearance of coronary calcium wherein subtle cardiac motion can be a useful artifact in the accurate detection of coronary calcium. In addition, we discuss correlating coronary calcium burden with age, elaborate on the physics behind coronary calcium detection, and how best to optimize imaging technique. Lastly, we show other uses of dual-energy lateral CXR technique to illustrate where using material decomposition and subtle motion can better define contours in the mediastinum and lung.
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http://dx.doi.org/10.1097/RCT.0000000000001318 | DOI Listing |
CJC Open
December 2024
University of British Columbia, Vancouver, British Columbia, Canada.
Background: Myocardial infarction with no obstructive coronary arteries (MINOCA), and ischemia with no obstructive coronary arteries (INOCA), are female-predominant conditions; clinical trials are lacking to guide medical management for the common underlying vasomotor etiologies. Data on long-term outcomes of (M)INOCA patients following attendance at a women's heart centre (WHC) are lacking.
Methods: Women diagnosed with MINOCA (n = 51) or INOCA (n = 112) were prospectively followed for 3 years at the Leslie Diamond WHC (LDWHC) in Vancouver.
Front Med (Lausanne)
December 2024
Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Background: This study investigated the association between coronary artery calcification (CAC) and triglyceride glucose-body mass index (TyG-BMI) in patients receiving maintenance hemodialysis (MHD).
Methods: We used computed tomography (CT) to assess coronary artery calcification score (CACS) using the Agatston method. The TyG index was multiplied by BMI to derive the TyG-BMI index.
Cureus
November 2024
General Surgery, Northeast Georgia Medical Center Gainesville, Gainesville, USA.
Coronary artery disease (CAD) remains a leading global cause of morbidity and mortality, underscoring the need for effective cardiovascular risk stratification and preventive strategies. Coronary artery calcium (CAC) scoring, traditionally performed using electrocardiogram (ECG)-gated cardiac computed tomography (CT) scans, has been widely validated as a robust tool for assessing cardiovascular risk. However, its application has been largely limited to high-risk populations due to the costs, technical requirements, and limited accessibility of cardiac CT scans.
View Article and Find Full Text PDFAACE Clin Case Rep
September 2024
Department of Medicine, Suburban Hospital, Johns Hopkins Medicine, Bethesda, Maryland.
Background/objective: Calcium channel blockers, when taken in overdose quantities, can cause hyperglycemia requiring so-called hyperinsulinemic-euglycemic therapy. The objective of this report was to describe a patient with calcium channel blocker toxicity resulting from overdose of amlodipine.
Case Report: A 74-year-old man presented with a fall and loss of consciousness.
Can J Cardiol
December 2024
Senior Paediatric Intensivist - Department of Paediatric Intensive Care, Royal Children's Hospital, Melbourne, Australia; Professor - Department of Critical Care, Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Melbourne, Australia; Group Leader - ICU Research Clinical Sciences Theme MCRI, Melbourne, Australia. Electronic address:
Nitric oxide (NO) was proclaimed the 1992 "molecule of the year" by Culotta in Science magazine because of its importance in neuroscience, physiology and immunology. Inhaled NO has been in clinical use for over 35 years to decrease pulmonary hypertension and improve oxygenation. Over the last 20 years there has been much research to understand the role of nitric oxide on cell surface receptors, mitochondria, and intracellular processes which involve calcium and superoxide radicals.
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