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Hemophagocytic Lymphohistiocytosis Associated With Epstein-Barr Virus Infection in an Immunocompetent Adult.
Cureus
December 2024
Department of Internal Medicine, Unidade Local de Saúde Entre Douro e Vouga, Santa Maria da Feira, PRT.
Hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal entity characterized by an unregulated activation of the immune system. In the adult population, it is most commonly secondary to infectious, autoimmune, or neoplastic diseases. We present a case of a 23-year-old female diagnosed with infectious mononucleosis and hospitalized due to a persistent three-week fever and malaise with a new onset of jaundice and findings compatible with acute hepatitis and hepatosplenomegaly.
View Article and Find Full Text PDFIntroduction: wrist ligament injuries and triangular fibrocartilage complex (TFCC) lesions are common but often underdiagnosed conditions causing chronic wrist pain. The diagnostic challenge necessitates a combination of clinical examination, imaging studies, and arthroscopy, considered the gold standard. Ligament injuries, particularly scapholunate ligament (SL), and TFCC lesions account for significant wrist instability and ulnar-sided wrist pain, respectively.
View Article and Find Full Text PDF[Association Between Balance Disorders, Fibromyalgia Severity, and Balance Confidence: An Observational Study on Fibromyalgia].
Rev Med Chil
July 2024
Universidad de Chile, Santiago de Chile, Chile.
Unlabelled: Fibromyalgia is a syndrome of widespread chronic pain, associated with fatigue, sleep disorders, and a wide range of additional symptoms, among which balance disorders are a common complaint.
Aim: To determine a correlation between balance disorders and severity of fibromyalgia.
Methods: An observational cross-sectional study was conducted at the Pain Treatment Unit of the Clinical Hospital of the University of Chile.
[Association Between Parkinson's Disease and Functionality in Older Adults in Chile: The Case of the Maipú Commune].
Rev Med Chil
July 2024
Núcleo de Envejecimiento de la Unidad de Nutrición Pública, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago, Chile.
Unlabelled: Population aging has caused a rise in neurodegenerative diseases among which includes Parkinson's disease. However, in Chile, there is still little knowledge about how Parkinson's disease is associated with functionality in elderly people.
Aim: to examine the association between Parkinson's disease and functionality in elderly people of Maipú, Metropolitan region, between the years 2017-2019.
Key features and guidelines for the application of microbial alpha diversity metrics.
Sci Rep
January 2025
Facultad de Ingeniería, Universidad Austral, LIDTUA, CIC, Buenos Aires, Argentina.
Studies of microbial communities vary widely in terms of analysis methods. In this growing field, the wide variety of diversity measures and lack of consistency make it harder to compare different studies. Most existing alpha diversity metrics are inherited from other disciplines and their assumptions are not always directly meaningful or true for microbiome data.
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