Comparison of the clinical and ultrasound evaluation of haemophilic arthropathy in children.

Gac Med Mex

Hematology Department, "Dr. Gaudencio González Garza" General Hospital, High Specialty Medical Unit, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Published: April 2022

AI Article Synopsis

  • The study investigates the effectiveness of the HEAD-US method for early detection of joint issues in children with haemophilia, which has not been extensively researched in the country.
  • It involved a longitudinal analysis of 69 pediatric patients, assessing joint condition using both clinical criteria (HJHS scale) and ultrasound across key joints like elbows, knees, and ankles.
  • Results indicated that the right knee had the highest ultrasound severity score, with significant correlations between the presence of inhibitors and joint involvement, while factors like age or type of haemophilia did not show as much impact.

Article Abstract

Background: Joint ultrasound examination using the HEAD-US method in the detection of early arthropathy is poorly studied in our country.

Objective: To compare the clinical and ultrasound evaluation of the joints in haemophilia.

Method: Longitudinal, prospective and descriptive study with paediatric patients with haemophilia A and B evaluated with the HJHS 2.1 scale and ultrasound with a linear transducer of 8 to 12 MHz. Elbows, knees and ankles joints were evaluated bilaterally, with HEAD-US protocol.

Results: 69 paediatric patients were included of which 48 with severe haemophilia A (weight: 40.1 kg). On the HJHS scale, a greater involvement was observed in the left knee (0.49), and less in the right ankle (0.05). With the HEAD-US scale, the most affected was the right knee (0.78). There is a significant relationship in the involvement of the right knee evaluated with the HEAD-US scale in the presence of inhibitor.

Conclusions: Weight above the 50 percentile is an independent risk factor for joint bleeding complications, while age and type of haemophilia do not appear to be related. The HEAD-US method is a useful and accessible tool for early detection of arthropathy and hemarthrosis.

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Source
http://dx.doi.org/10.24875/GMM.M22000634DOI Listing

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