AI Article Synopsis
- This study aimed to assess changes in the retina and choroid of children who had COVID-19, using optical coherence tomography (OCT) and OCT angiography (OCTA).
- The research compared pediatric COVID-19 patients with healthy controls, measuring vessel density (VD), central macular thickness, and choroidal thickness (ChT) 12 weeks after recovery.
- The findings indicated that while both VD and ChT were lower in COVID-19 patients compared to controls, these differences were not statistically significant, suggesting OCTA could be a useful tool for detecting early vascular issues linked to COVID-19.
Article Abstract
Purpose: To analyze structural and vascular changes of the retina and choroid in pediatric patients with coronavirus disease 2019 (COVID-19) using optical coherence tomography (OCT)/OCT angiography (OCTA).
Methods: This comparative cross-sectional study consists of the COVID-19 group including pediatric COVID-19 patients and the control group including healthy children. Vessel density (VD), central macular thickness,, and choroidal thickness (ChT) measurements were performed using swept-source OCT/OCTA 12 weeks after the recovery from COVID-19.
Results: The mean VD measurements in the central fovea and nasal quadrants of all three retinal layers and choriocapillaris showed insignificantly lower values in the COVID-19 group when compared to the control group (0:002 < p < 0:05 for all). Similar to VD measurements, insignificant lower ChT measurements were obtained in the central fovea and nasal points in the COVID-19 group.
Conclusion: OCTA can be used as a non-invasive and valid biomarker in the assessment of early microvascular dysfunction associated with COVID-19.
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| http://dx.doi.org/10.1080/09273948.2022.2054431 | DOI Listing |
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