The diagnosis of trigger finger (TF) in patients who do not demonstrate triggering at presentation can be challenging. We have been using a new test for TF - the Lenox Independent Flexion Test (LIFT). The aim of this study is to determine the sensitivity of LIFT in diagnosing TF. We hypothesise that LIFT will be more sensitive compared to the classic physical exam finding of triggering or locking with active range of motion (AROM). This is a prospective study of consecutive patients with TF over a 5-month period. Patients with the onset of trigger following trauma and trigger of the thumb were excluded. Patients were examined for tenderness over the first annular (A1) pulley, triggering or locking with AROM, and the LIFT was performed. A two-proportion test was used to determine whether the LIFT was more sensitive than triggering with AROM. The study included 85 patients with 118 TFs. The average age of patients was 63 years and the study included 49 women. There were 69, 49, 0 and 0 grade I, II, III and IV TF, respectively. 108 fingers (92%) had a history of catching or locking of the affected digit, 110 (93%) had tenderness over the A1 pulley, 49 (44%) had triggering or locking with AROM and 102 (91%) had a positive LIFT. The LIFT was found to be more sensitive when compared to triggering with AROM ( < .001). The LIFT is more sensitive than triggering with AROM in the diagnosis of trigger digits. This test is especially useful in the diagnosis of TF in patients who do not have triggering at presentation. Level III (Diagnostic).
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http://dx.doi.org/10.1142/S2424835522500369 | DOI Listing |
Adv Healthc Mater
December 2024
State Key Laboratory of Bio-fibers and Eco-textiles, Institute of Biochemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao, 266071, China.
Interference with glycolysis metabolism not only promotes the efficient sensitization of cuproptosis, but also amplifies cytotoxic T cell functions and proliferations, thus contributing to relieve immunosuppressive tumor microenvironment. However, the synergistic mechanism and the design of multicomponent nanoformulations involving these three pathways have not yet been explored. a copper-coordinated nanoassembly (designated as Cu-GM) is reported here that integrates a lactate dehydrogenase inhibitor, galloflavin (GF), with an immune checkpoint inhibitor, myricetin (MY), to boost cancer cuproptosis-immunotherapy.
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December 2024
School of Human Kinetics, University of Ottawa, 200 Lees Ave, Ottawa, ON K1N 6N5, Canada. Electronic address:
The ability to perceive a tactile stimulus is reduced in a moving limb, a phenomenon known as tactile suppression. This sensory attenuation effect is attributed to movement-related gating, which allows the central nervous system to selectively process sensory information. However, the source of this gating is uncertain, with some evidence suggesting a forward-model origin of tactile suppression, and other evidence in support of backward masking from peripheral reafference.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
College of Textile Science and Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi 214222, China.
Stiffness change materials have been widely used in soft robots, intelligent adhesives and biomedical minimally invasive devices which can respond to specific stimuli. Compared with stimuli such as light, electricity, magnetism, temperature, and pressure, moisture is a non-toxic, readily available, and inexhaustible triggered source in the atmosphere. However, it is challenging to achieve a stiffness variable material with a large stiffness change using moisture.
View Article and Find Full Text PDFNanophotonics
April 2024
CNR-INO - Istituto Nazionale di Ottica, Via Carrara, 1 - 50019, Sesto Fiorentino FI, Italy.
Since the beginning of this millennium, frequency comb generators have reshaped frequency metrology and related areas. After more than two decades since their first realization, several other ways to generate frequency combs, in any spectral region, have been demonstrated, each way with its peculiar features. This trend has triggered the need to quantitatively assess how close the new comb realizations are to an ideal comb, a feature that will be called combness throughout this paper.
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