AI Article Synopsis
- The analysis of odorous volatile thiols is challenging, with progress made in quantifying them but less focus on identifying unknown thiols.
- A solid-phase extraction (SPE) method using a silver ion-based sorbent effectively isolates these thiols from red wine, achieving high recovery rates and minimizing artifacts.
- The method utilizes heart-cutting multidimensional gas chromatography coupled with mass spectrometry/olfactometry for optimal separation and detection, demonstrated in two case studies for qualitative screening of thiols in wine.
Article Abstract
The chemical analysis of odorous volatile thiols is intrinsically challenging. Substantial progress has been made in quantitative analysis of targeted thiols at ultra-trace concentrations (ng/L), but lesser analytical attention has been given to the qualitative screening of unknown thiols. This work presents a solid-phase extraction (SPE) method using a silver ion (Ag)-based sorbent to isolate volatile thiols from red wine. This proposed Ag SPE method was effective (recovery: 87-101% for four non-furan thiols and 35-49% for two furan thiols), simple, safe, and greatly reduced artifacts, testifying to its suitability as the sample preparation protocol for a qualitative screening experiment. Separation and detection were conducted using heart-cutting multidimensional gas chromatography coupled to mass spectrometry/olfactometry (H/C MDGC-MS/O). Key parameters including H/C width, main host oven temperature, and cryogenic trapping temperature were investigated for optimal instrument performance. The developed Ag SPE H/C MDGC-MS/O strategy was readily applicable for qualitative screening of odorous volatile thiols in wine, as demonstrated by two case studies.
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| http://dx.doi.org/10.1021/acs.jafc.2c00243 | DOI Listing |
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