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| http://dx.doi.org/10.1016/j.resplu.2022.100224 | DOI Listing |
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The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case-control and bias indicator study.
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Geneva Centre for Emerging Viral Diseases, Geneva University Hospitals, Geneva, Switzerland; Médecins Sans Frontières, Geneva, Switzerland; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Division of Tropical and Humanitarian Medicine, Geneva University Hospitals, Geneva, Switzerland. Electronic address:
Background: Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalent. Although a recombinant vaccine, Hecolin, is available, it has not been used to control outbreaks. The licensed three-dose regimen might pose challenges for it to be an impactful outbreak control tool.
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Julius Kühn Institute (JKI), Federal Research Centre for Cultivated Plants, Institute for Grapevine Breeding Geilweilerhof, 76833, Siebeldingen, Germany.
The hairiness of the leaves is an essential morphological feature within the genus Vitis that can serve as a physical barrier. A high leaf hair density present on the abaxial surface of the grapevine leaves influences their wettability by repelling forces, thus preventing pathogen attack such as downy mildew and anthracnose. Moreover, leaf hairs as a favorable habitat may considerably affect the abundance of biological control agents.
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Department of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.
Solenogastres is a group of mollusks with evolutionary and ecological importance. Nevertheless, their diversity is underestimated and knowledge about the distribution of the approximately 300 formally described species is limited. Factors that contribute to this include their small size and frequent misidentification by non-specialists.
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