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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974882 | PMC |
http://dx.doi.org/10.1002/mdc3.13427 | DOI Listing |
Curr Opin Neurol
June 2019
Department of Oncology.
Purpose Of Review: Immune checkpoint inhibitors (ICPI) and chimeric antigen receptor T cells (CAR-T) represent novel therapies recently approved to treat a number of human cancers. As both approaches modulate the immune system, they can generate a number of immune-related adverse events (irAEs), including a large spectrum of novel neurological toxicities. These are of special interest given their potential severity and risk of compromising further oncologic treatment.
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