AI Article Synopsis
- Cardiovascular disease is a leading cause of death for people.
- Cytokines, which are special proteins in our body, are important in the development of these heart diseases.
- The review focuses on a group of cytokines called the IL-6 family, explaining how they relate to heart problems and looking for ways to prevent or treat these diseases.
Article Abstract
Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a series of cytokines, including IL-6, IL-11, IL-30, IL-31, OSM, LIF, CNTF, CT-1, CT-2, and CLC, that regulate multiple biological effects. Experimental and clinical evidence shows that IL-6 family members are closely related to cardiovascular diseases such as atherosclerosis, hypertension, aortic dissection, cardiac fibrosis, and cardiomyopathy. This review mainly discusses the role of IL-6 family members in cardiovascular disease for the sake of identifying possible intervention targets for cardiovascular disease prevention and treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983865 | PMC |
| http://dx.doi.org/10.3389/fcvm.2022.818890 | DOI Listing |
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