AI Article Synopsis
- Wheezing, asthma, and respiratory infections (RTI) significantly affect children's health, and there's potential for reducing their impact through targeted prevention strategies.
- The review investigates the effects of early supplementation with nutrients like pre- and probiotics, vitamin D, and fish oils during the first year of life on the prevention of these conditions.
- Findings suggest that while pre- and probiotics generally lack protective effects for asthma and wheezing, vitamin D may help prevent RTI, and early fish introduction in the diet appears beneficial against wheezing and asthma development.
Article Abstract
Wheezing, asthma, and respiratory infections (RTI) are among the most common causes of morbidity in children and their economic and social burden could be significantly reduced by specific prevention strategies. Epidemiological studies suggest that lower levels of some nutrients are associated with higher prevalence of these conditions, but the possible protective effect of early supplementation with these nutrients has not yet been established. Aim of our review is to synthetize the available scientific evidence on the role of supplementation with pre- and probiotics, vitamin D, fish and poly-unsaturated fatty acids (PUFA), vitamin A, C, and E, given during the first year of life, in the prevention of wheezing, asthma and RTI. We searched studies published on this topic in the PubMed database between January 2000 and September 2021. As for pre- and probiotics, most of the studies showed that an early supplementation had no protective effect toward the development of asthma and wheezing, while conflicting results were reported on their role in the reduction of RTI. As for vitamin D, the available data suggest that early and regular (on a daily or weekly base) supplementation of vitamin D during infancy could have a role in the prevention of RTI, while most studies showed no effect in the prevention of wheezing or asthma. Finally, early introduction of fish in the diet in most studies has proved protective toward wheezing and asthma development.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990313 | PMC |
| http://dx.doi.org/10.3389/fped.2022.866868 | DOI Listing |
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