The management of deep carious lesions in immature tooth and the preservation of its pulp vitality is a real challenge in daily dental practice. Bioactive cements are of interest to deal with such cases. Our case report describes the immediate management and the follow-up of an extensive carious lesion on an immature first right mandibular molar with pulp exposure by direct pulp capping using Biodentine. A 6-month clinical and radiographic follow up showed that the tooth was vital, with dentine-bridge formation in the pulp chamber with continuous root formation. This procedure allowed the protection of pulp complex, preserving at the same time its functional and biologic activities due to the capacities of Biodentine as an effective pulp capping material to induce pulp cells to form hard tissue. The aim of this article is to discuss through the report of this clinical case, the indications, advantages and disadvantages of different procedures and biomaterials used for direct pulp capping.
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http://dx.doi.org/10.1177/2050313X221087565 | DOI Listing |
Nanoscale
January 2025
State Key Laboratory of Biobased Fiber Manufacturing Technology, Tianjin Key Laboratory of Pulp and Paper, China Light Industry Key Laboratory of Papermaking and Biorefinery, Tianjin University of Science and Technology, No. 29, 13th Street, TEDA, Tianjin 300457, P. R. China.
The remarkable catalytic activity, optical properties, and electrochemical behavior of nanomaterials based on noble metals (NM) are profoundly influenced by their physical characteristics, including particle size, morphology, and crystal structure. Effective regulation of these parameters necessitates a refined methodology. Lignin, a natural aromatic compound abundant in hydroxyl, carbonyl, carboxyl, and sulfonic acid groups, has emerged as an eco-friendly surfactant, reducing agent, and dispersant, offering the potential to precisely control the particle size and morphology of NM-based nanomaterials.
View Article and Find Full Text PDFJ Dent
December 2024
Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. Electronic address:
Objectives: To evaluate the multifunctionality of silver-copper co-loaded mesoporous bioactive glass (MBG), with the goal of developing an advanced pulp-capping material.
Methods: The synthesis of materials was conducted using the sol-gel method, following the approach described in previous studies but with some modifications. The composition included 80 mol% SiO₂, 15 mol% CaO, and 5 mol% P₂O₅, with additional components of 5 mol% silver, 5 mol% copper, or 1 mol% silver combined with 4 mol% copper, designated as Ag5/80S, Cu5/80S, or Ag1Cu4/80S, respectively.
bioRxiv
December 2024
Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago 60612, IL, USA.
Dental caries is one of the most common health issues worldwide arising from the complex interactions of bacteria. In response to harmful stimuli, desirable outcome for the tooth is the formation of tertiary dentin, a protective reparative process that generates new hard tissue. This reparative dentinogenesis is associated with significant inflammation, which triggers the recruitment and differentiation of dental pulp stem cells (DPSCs).
View Article and Find Full Text PDFJ Dent (Shiraz)
December 2024
ENT and Head and Neck Research Center and Department, The five senses Health Institute, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Statement Of The Problem: Success of pulpotomy of primary teeth depends on biological and cytotoxic effects of pulp capping agents. Mineral trioxide aggregate (MTA), Biodentine, calcium enriched mixture (CEM) cement, and ferric sulfate (FS) are among the commonly used pulp capping agents (PCAs) for pulpotomy, and their successful application has been previously evaluated.
Purpose: This study aimed to compare the cytotoxicity of PCAs against mesenchymal stem cells isolated from human exfoliated deciduous teeth (SHEDs).
Eur Endod J
December 2024
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
Objective: To evaluate the effect of a newly developed MTA-based material and two antibacterial-enhanced MTAs as pulp capping materials in immature permanent dental elements underwent full pulpotomy.
Methods: The present animal study included 20 Wistar albino rats that, after full pulpotomy, were randomly divided into 4 groups receiving different MTA formulations as pulp capping materials: conventional MTA, Tricalcium aluminate (TCA)- free MTA, and MTA enhanced with metronidazole or doxycycline. Histopathological assessments were carried out at 7- and 28-days post-treatment to evaluate dentinal bridge formation, inflammatory reactions, pulp tissue necrosis and internal resorption.
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