Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.rdc.2022.03.002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration.
Nucleic Acids Res
December 2024
Bioinformatics Group, Wageningen University & Research, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readable way, the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard and repository was initiated in 2015.
View Article and Find Full Text PDFSNP Fingerprinting for Germplasm Identification of the Fast-Growing Pacific oyster (Crassostrea gigas) "Haida No. 1" Variety.
Mar Biotechnol (NY)
November 2024
Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao, 266003, China.
The Pacific oyster (Crassostrea gigas) is a global aquaculture species of economic significance. Selective breeding programs have been conducted to produce multiple strains with fast growth as well as other desirable traits. However, due to the phenotypic plasticity of oysters, challenges existed for precise germplasm identification among selectively bred strains.
View Article and Find Full Text PDFEmploying a switching valve to automate external standard calibration in inductively coupled plasma optical emission spectrometry.
Talanta
December 2024
Department of Chemistry, Wake Forest University, Salem Hall, Box 7486, Winston-Salem, NC, 27109, United States. Electronic address:
The traditional external standard calibration method (EC) is automated and simplified using a four-port switching valve (SV4) and a multi-signal approach that enables the generation of several calibration points from a single calibration solution. The SV4-EC method is applied to inductively coupled plasma optical emission spectrometry (ICP-OES) and is based on gradient dilution taking place within the instrument's sample introduction tubing. Both the calibration solution and the samples are diluted by a blank solution containing an internal standard species.
View Article and Find Full Text PDFLong term rescue of Alzheimer's deficits by one-time gene-editing of C-terminus.
bioRxiv
June 2024
Department of Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, USA.
Gene-editing technologies promise to create a new class of therapeutics that can achieve permanent correction with a single intervention. Besides eliminating mutant alleles in familial disease, gene-editing can also be used to favorably manipulate upstream pathophysiologic events and alter disease-course in wider patient populations, but few such feasible therapeutic avenues have been reported. Here we use CRISPR-Cas9 to edit the last exon of amyloid precursor protein (), relevant for Alzheimer's disease (AD).
View Article and Find Full Text PDFStudy on static and dynamic mechanical behavior of expansive soil modified by oyster shell powder.
Heliyon
April 2024
School of Civil Engineering and Architecture, Guangxi University, Nanning, 530004, China.
To investigate the effect of oyster shell powder (OSP) on the static and dynamic properties of expansive soil, the mechanical properties of modified soil were obtained. Taking Ningming expansive soil as the research object, triaxial shear test, dynamic triaxial test and scanning electron microscope test were carried out on plain soil and 9 % expansive soil modified by oyster shell powder (ESMO). The results show that compared with plain soil, the effective cohesion of modified expansive soil with < 1 mm (ESMO ( < 1 mm)) and < 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!