Background: The antibacterial activity of restorative material and the amount of fluoride released are interlinked. Hence, these are the two foremost properties to be studied.
Aim: This study aimed to evaluate and compare the amount and pattern of fluoride release from Type IX GIC (GC HS posterior), nanoionomer (Ketac N100), and alkasite (Cention N), and the antibacterial activity against at 24 and 48 h.
Settings And Design: This study was carried out in laboratory settings with six samples of each group for fluoride release using an ion-chromatography (IC) machine and five samples of each group for antibacterial activity using agar plates.
Materials And Methodology: Samples of each group, Group I - Type IX GIC, Group II - nanoionomer, and Group III -alkasite, were prepared, immersed in 2 ml of artificial saliva, and fluoride release recorded using IC after 1, 7, 14, and 28 days intervals. The antibacterial activity against was evaluated by placing samples of each group in the agar plates and measuring the diameter of zones of inhibition after 24 and 48 h.
Statistical Analysis: One-way ANOVA test to check to mean differences between the groups and Tukey's honestly significant difference test for multiple intergroup comparisons ( = 0.05).
Results: The Type IX GIC showed the highest fluoride release after day1. However, nanoionomer showed the maximum fluoride release for the remaining days. The least amount of fluoride released was from the alkasite throughout the study. The antibacterial activity of nanoionomer was the highest, followed by Type IX GIC and alkasite at both 24 and 48 h.
Conclusions: Nanoionomer showed the highest fluoride release and antibacterial activity.
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http://dx.doi.org/10.4103/jcd.jcd_336_21 | DOI Listing |
J Dent Sci
December 2024
Faculty of Dentistry, The University of Hong Kong, Hong Kong, S.A.R., China.
The World Health Organization (WHO) has added glass ionomer cement (GIC) to the WHO Model List of Essential Medicines since 2021, which represents the most efficacious, safe and cost-effective medicines for priority conditions. With the potential increase in the use of GIC, this review aims to provide an overview of the clinical application of GIC with updated evidence in restorative and preventive dentistry. GIC is a versatile dental material that has a wide range of clinical applications, particularly in restorative and preventive dentistry.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Faculty of Technology and Metallurgy, University of Belgrade, 11000 Belgrade, Serbia.
Sci Rep
January 2025
Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
The main objective of the current study is to compare short-term fluoride release of three ion releasing restorative materials and assess their inhibitory effect on secondary caries. Materials used in this study included, Self-adhesive hybrid composite (group A), Ion releasing flowable composite liner (group B), and alkasite restorative material (group C). Twenty-two discs were fabricated from each material for short-term fluoride release test, conducted on days 1, 7, and 14.
View Article and Find Full Text PDFEnviron Geochem Health
January 2025
Ecosphere Resilience Research Centre, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250, Sri Lanka.
Studies regarding geochemical partitioning and leaching behavior of Hofmeister ions, which is considered as a risk/causative factor for chronic kidney disease of unknown etiology (CKDu), are scarce. Therefore, Hofmeister ions' leaching behavior of partially weathered rocks from CKDu endemic (Girandurukotte) and non-endemic (Sewanagala) areas, Sri Lanka were compared. Rock mineralogy was analyzed using X-ray Diffraction, and total ion contents were determined using alkaline and acid digestions.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China.
Dental caries, driven by dysbiosis in oral flora and acid accumulation, pose a significant threat to oral health. Traditional methods of managing dental biofilms using broad-spectrum antimicrobials and fluoride face limitations such as microbial resistance. Natural products, with their antimicrobial properties, present a promising solution for managing dental caries, yet their clinical application faces significant challenges, including low bioavailability, variable efficacy, and patient resistance due to sensory properties.
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