Interdigitating dendritic cell sarcoma (IDCS) is a rare, highly malignant tumor with a poor prognosis, and current knowledge of this tumor is limited. It is reported that lymph nodes are the primary localization sites. However, in recent years, many primary IDCS have also been reported in the extra-nodal sites, which undoubtedly increases the difficulty of diagnosis. There are very few reports that systematically analyze the clinicopathologic features of IDCS. Here we described two cases of extra-nodal IDCS and reviewed the literature of 44 other published cases of extra-nodal IDCS. Thus, the clinical symptoms, pathological diagnosis, and therapeutic effects of 46 cases of extra-nodal IDCS were summarized in detail. Considering the paucity of available data with regard to IDCS, a thorough and detailed summary would help to better diagnose and treat this neoplasm.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00428-022-03320-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
CD23 expression in lymphoplasmacytic lymphoma: Clinical-pathological and biological correlations.
Histopathology
December 2024
Pathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy.
Aims: The diagnosis of lymphoplasmacytic lymphoma (LPL) in the bone marrow (BM) is challenged by aberrant phenotypes and by overlapping histological features with marginal zone lymphoma (MZL). To address these issues, we (i) assessed LPL immunophenotype on a large series of BM samples, (ii) drew possible correlations between LPL phenotype and clinical/molecular data and (iii) investigated the role of new phenotypical markers in the differential diagnosis between LPL and MZL.
Materials And Methods: The study retrospectively considered 81 clinically annotated LPL diagnosed at Padua University Hospital (Padua, Italy) during a 5-year period.
Primary Extra-nodal Diffuse Large B-cell Lymphoma of the Gingiva Mimicking a Dental Abscess: A Diagnostic Challenge.
Cureus
November 2024
Oral Surgery, Faculty of Dentistry, Paris City University, Paris, FRA.
Lymphomas are malignant proliferations of B or T lymphocytes, classified as Hodgkin or non-Hodgkin lymphomas. The malignant proliferation of lymphoid cells mainly occurs in lymph nodes, but in a small number of cases, it can be extranodal. The oral cavity represents a very rare primary extra-nodal location for non-Hodgkin lymphoma and can pose a diagnostic challenge for the dentist.
View Article and Find Full Text PDFExploration of the value of concurrent chemotherapy for T2N1 nasopharyngeal carcinoma under intensity modulated radiotherapy mode.
Front Oncol
November 2024
Department of Radiotherapy, Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, China.
Article Synopsis
- The study investigates the effectiveness of concurrent chemoradiotherapy (CCRT) compared to intensity-modulated radiation therapy (IMRT) for treating stage II nasopharyngeal carcinoma (NPC), focusing on T2N1 subtype patients.
- A total of 218 patients were analyzed, showing no significant differences in long-term survival rates between the IMRT and CCRT groups, although certain factors like EBV DNA levels and lymph node necrosis influenced prognosis.
- Results suggest that while both treatment methods are similar in effectiveness overall, CCRT has a higher rate of acute side effects, particularly in patients with lymph node necrosis.
Cardiac Tamponade Due to Diffuse Large B-cell Lymphoma/Plasmablastic Lymphoma in an Immunocompetent Patient.
Cureus
November 2024
Internal Medicine, St Mary Medical Center, Langhorne, USA.
Article Synopsis
- * It typically occurs in males and is characterized by extra-nodal masses, often found in the oral cavity or gastrointestinal tract, but a unique case involved a 93-year-old female without HIV showing pericardial effusion instead.
- * Diagnosis of PBL can be challenging due to atypical presentations; thus, awareness, thorough immunohistochemistry, and clinical correlation are critical for accurate identification.
A Rare Case of Extra-Nodal Rosai-Dorfman Disease of the Cheek.
J Nippon Med Sch
November 2024
Department of Plastic Surgery, Nippon Medical School Musashi Kosugi Hospital.
Rosai-Dorfman disease (RDD), which was first reported by Rosai and Dorfman in 1969, is a rare, benign, non-neoplastic proliferation of histiocytes, characterized by painless lymphadenopathy and fever. Lymphadenopathy occurs most commonly in the neck, but also appears in non-cervical lymph nodes or as extranodal lesions. In this case, biopsy of an atypical subcutaneous buccal mass, which was difficult to diagnose preoperatively, led to a diagnosis of RDD.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!