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Enhancing semantical text understanding with fine-tuned large language models: A case study on Quora Question Pair duplicate identification.
PLoS One
January 2025
Department of Biomedical and Health Informatics, Tsui Laboratory, Children's Hospital of Philadelphia, Philadelphia, PA, United States of America.
Semantical text understanding holds significant importance in natural language processing (NLP). Numerous datasets, such as Quora Question Pairs (QQP), have been devised for this purpose. In our previous study, we developed a Siamese Convolutional Neural Network (S-CNN) that achieved an F1 score of 82.
View Article and Find Full Text PDFderived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications.
Virulence
December 2025
Henan International Joint Laboratory of Children's Infectious Diseases, Department of Neonatology, Henan Province Engineering Research Center of Diagnosis and Treatment of Pediatric Infection and Critical Care, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
is a gram-negative pathogen that can cause multiple diseases including sepsis, urinary tract infections, and pneumonia. The escalating detections of hypervirulent and antibiotic-resistant isolates are giving rise to growing public concerns. Outer membrane vesicles (OMVs) are spherical vesicles containing bioactive substances including lipopolysaccharides, peptidoglycans, periplasmic and cytoplasmic proteins, and nucleic acids.
View Article and Find Full Text PDFAgency - the capacity to produce an effect - is a foundational aspect of medical education. Agency is usually conceptualized at the level of the , with each learner charged with taking responsibility to pull themselves up by their bootstraps. This conceptualization is problematic.
View Article and Find Full Text PDFEpidemiology of Soft Tissue Sarcoma in Iran: Four-Year National Cancer Registry Data Report (2014-2017).
Cancer Rep (Hoboken)
January 2025
MD, Assistant Professor in Community Medicine, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Introduction: An uncommon and diverse class of cancers originating from mesenchymal tissues is designated as soft tissue sarcoma (STS). To develop effective preventive and treatment strategies for STS, it is essential to gain a deeper understanding of the epidemiological trends associated with the disease. This research will analyze the 4-year age-standardized incidence rate (ASIR) and geographical distribution of STS in Iran in great detail.
View Article and Find Full Text PDFThe Challenges Associated with : Barriers to Implementing Naturalistic Developmental Behavioral Interventions in ABA Settings.
Behav Anal Pract
December 2024
Department of Pediatrics, Division of Autism and Related Disabilities, Emory School of Medicine, 1920 Briarcliff Road, Atlanta, GA 30329 USA.
Unlabelled: Naturalistic developmental behavioral intervention (NDBI) supports early social communication skills in young autistic children. Given their emphasis on child-led learning opportunities, NDBI is thought to be a socially valid approach to autism early intervention. Applied behavior analysis (ABA) practices could be an ideal setting to increase access to NDBIs for young autistic children; however, current ABA services continue to rely primarily on structured and adult-led approaches to teaching, including discrete trial training (DTT), which have been criticized for their intensity, limitations in skill generalization, and possible harms.
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